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经皮射频与酒精消融联合治疗骨样骨瘤

Percutaneous osteoid osteoma treatment with combination of radiofrequency and alcohol ablation.

作者信息

Akhlaghpoor S, Tomasian A, Arjmand Shabestari A, Ebrahimi M, Alinaghizadeh M R

机构信息

Noor Medical Imaging Center, Tehran, Iran.

出版信息

Clin Radiol. 2007 Mar;62(3):268-73. doi: 10.1016/j.crad.2006.08.017.

Abstract

AIM

To assess the efficacy of percutaneous osteoid osteoma treatment using a combination of radiofrequency ablation (RFA) and alcohol ablation with regard to technical and long-term clinical success.

MATERIALS AND METHODS

From December 2001 to November 2004, RFA and subsequent alcohol ablation was performed on 54 patients with osteoid osteoma, diagnosed clinically using radiography, computed tomography (CT) and symptoms. Under general anaesthesia, treatment was performed via percutaneous access under thin section (2mm) spiral CT guidance in all cases with an 11 G radiofrequency-compatible coaxial needle and 2mm coaxial drill system and 1.0 cm active tip 17 G non-cooled radiofrequency needle. RFA was performed at 90 degrees C for a period of 6 min. After needle removal, 0.5-1.0 ml absolute alcohol (99.8% concentration) was injected directly into the nidus using a 20 G needle. Patients were discharged within 24h and followed up clinically (at 1 week, 1 month and every 3 months thereafter).

RESULTS

The technical success rate was 100%. Complications occurred in two patients consisting of local mild cellulitis in entry site and peripheral small zone paresthesia on the anterior part of leg. The follow-up period range was 13-48 months (mean+/-SD, 28.2+/-7.4 months). Prompt pain relief and return to normal activities were observed in 52 of 54 patients. Recurrent pain occurred in two patients after a 1 and 3 months period of being pain free, respectively; a second RFA and alcohol ablation was performed achieving successful results. Primary and secondary clinical success rates were 96.3% (52/54 patients) and 100% (2/2 patients), respectively.

CONCLUSION

Percutaneous osteoid osteoma treatment with combination of radiofrequency and alcohol ablation is safe, effective and minimally invasive with high primary and secondary success rates. Persistent or recurrent lesions can be effectively re-treated.

摘要

目的

评估射频消融(RFA)联合酒精消融治疗骨样骨瘤在技术及长期临床疗效方面的效果。

材料与方法

2001年12月至2004年11月,对54例经X线摄影、计算机断层扫描(CT)及症状临床诊断为骨样骨瘤的患者进行RFA及后续酒精消融治疗。所有病例均在全身麻醉下,通过细层(2mm)螺旋CT引导经皮穿刺,使用11G射频兼容同轴针、2mm同轴钻系统及1.0cm有效尖端的17G非冷却射频针进行治疗。RFA在90℃下进行6分钟。拔针后,使用20G针将0.5 - 1.0ml无水乙醇(浓度99.8%)直接注入瘤巢。患者在24小时内出院,并进行临床随访(术后1周、1个月及此后每3个月)。

结果

技术成功率为100%。两名患者出现并发症,包括穿刺部位局部轻度蜂窝织炎及小腿前部外周小区域感觉异常。随访期为13 - 48个月(平均±标准差,28.2±7.4个月)。54例患者中有52例疼痛迅速缓解并恢复正常活动。两名患者在无痛1个月和3个月后分别出现复发性疼痛;再次进行RFA及酒精消融取得成功。原发性和继发性临床成功率分别为96.3%(52/54例患者)和100%(2/2例患者)。

结论

射频联合酒精消融经皮治疗骨样骨瘤安全、有效且微创,原发性和继发性成功率高。持续性或复发性病变可得到有效再治疗。

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