Zusman Alexander S, Baltimore Robert S, Fonseca Silvia N S
Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT, USA.
Braz J Infect Dis. 2006 Aug;10(4):242-6. doi: 10.1590/s1413-86702006000400005.
The objective of this study was to determine the prevalence of maternal group B Streptococcal (GBS) colonization and compare risk factor data related to GBS colonization. A prospective surveillance study of 598 pregnant women was conducted in two socioeconomically diverse maternity hospitals in Ribeirão Preto, Brazil between June and October 1999. Swabs from the lower vagina were obtained between 35 and 37 weeks gestation and cultured on selective media. Risk factor data were obtained by patient interview and chart review. The overall maternal GBS colonization prevalence rate was 17.9%. There was no association of GBS colonization with maternity hospital and no association of GBS colonization with previously identified risk factors, such as age, race, martial status, maternal education, parity, smoking, or alcohol use. There is a relatively high prevalence of maternal GBS colonization in this Brazilian population, although previously-identified-risk factors were not found to be important. This study provides baseline data for the creation of community-based GBS disease prevention protocols.
本研究的目的是确定孕妇B族链球菌(GBS)定植的患病率,并比较与GBS定植相关的危险因素数据。1999年6月至10月期间,在巴西里贝朗普雷图两所社会经济情况不同的妇产医院对598名孕妇进行了一项前瞻性监测研究。在妊娠35至37周之间采集阴道下段拭子,并在选择性培养基上培养。通过患者访谈和病历审查获取危险因素数据。孕妇GBS定植的总体患病率为17.9%。GBS定植与妇产医院无关,也与先前确定的危险因素如年龄、种族、婚姻状况、产妇教育程度、产次、吸烟或饮酒无关。尽管先前确定的危险因素并不重要,但该巴西人群中孕妇GBS定植的患病率相对较高。本研究为制定基于社区的GBS疾病预防方案提供了基线数据。