Lion Y, Saucin M, Van de Vorst A
Radiat Environ Biophys. 1975 Dec 4;12(4):337-44. doi: 10.1007/BF01323421.
The evolution of the proflavine triplet state population with the extent of aggregation is examines, by ESRmeasurements, as a function of organic solvents and mineral salts, well known for their ability to influence the aggregation process. The intensity of the triplet state population has also been investigated as a function of pH. The insertion of aromatic molecules like DNA's nucleotides between dye molecules is shown to increase the intensity of the triplet state. It is put forward that the observed triplet state is characteristic of the singly protonated proflavine which seems to be the active species in in vivo experiments.
通过电子自旋共振（ESR）测量，研究了硫酸原黄素三重态布居随聚集程度的演变，该演变是有机溶剂和无机盐的函数，而有机溶剂和无机盐因其影响聚集过程的能力而广为人知。还研究了三重态布居强度随pH值的变化。结果表明，DNA核苷酸等芳香分子插入染料分子之间会增加三重态的强度。有人提出，观察到的三重态是单质子化硫酸原黄素的特征，而单质子化硫酸原黄素似乎是体内实验中的活性物质。
