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男性压力性尿失禁的保守治疗

[Conservative treatment of male stress incontinence].

作者信息

Buse S, Reitz A, Haferkamp A, Hohenfellner M

机构信息

Urologische Universitätsklinik, Ruprecht-Karls-Universität, Im Neuenheimer Feld 110, 69121, Heidelberg, Deutschland.

出版信息

Urologe A. 2007 Mar;46(3):240-3. doi: 10.1007/s00120-007-1296-7.

DOI:10.1007/s00120-007-1296-7
PMID:17294152
Abstract

The majority of male patients affected by stress incontinence developed this disturbance after radical prostatectomy or less frequently after TURP. Urodynamic evaluation shows sphincter insufficiency in more than 90% of the patients. The conservative therapy of postprostatectomy stress incontinence relies on physical methods, namely, pelvic floor muscle training with or without electrical or magnetic stimulation. However, evidence in favor of one or the other approach is limited. Since publication of the positive results with duloxetine in women, interest in medical therapy for men reporting postoperative stress incontinence has increased. Conclusive evidence in favor of duloxetine for prostatectomy-associated incontinence however is still missing.

摘要

大多数患有压力性尿失禁的男性患者在根治性前列腺切除术后出现这种紊乱,较少情况下在经尿道前列腺电切术后出现。尿动力学评估显示,超过90%的患者存在括约肌功能不全。前列腺切除术后压力性尿失禁的保守治疗依赖于物理方法,即盆底肌肉训练,可伴有或不伴有电刺激或磁刺激。然而,支持一种或另一种方法的证据有限。自从度洛西汀在女性中取得阳性结果的报道发表以来,对报告术后压力性尿失禁的男性进行药物治疗的兴趣有所增加。然而,仍然缺乏支持度洛西汀治疗前列腺切除术后尿失禁的确凿证据。

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引用本文的文献

1
[Conservative management of postoperative urinary incontinence in men].男性术后尿失禁的保守治疗
Urologe A. 2010 Apr;49(4):498-503. doi: 10.1007/s00120-010-2264-1.

本文引用的文献

1
Duloxetine, a serotonin and noradrenaline reuptake inhibitor (SNRI) for the treatment of stress urinary incontinence: a systematic review.度洛西汀,一种用于治疗压力性尿失禁的5-羟色胺和去甲肾上腺素再摄取抑制剂(SNRI):一项系统评价
Eur Urol. 2007 Jan;51(1):67-74. doi: 10.1016/j.eururo.2006.08.041. Epub 2006 Sep 15.
2
Pharmacologic treatment in postprostatectomy stress urinary incontinence.前列腺切除术后压力性尿失禁的药物治疗
Eur Urol. 2007 Jun;51(6):1559-64. doi: 10.1016/j.eururo.2006.08.005. Epub 2006 Aug 15.
3
Is HCl duloxetine effective in the management of urinary stress incontinence after radical prostatectomy?
盐酸度洛西汀在根治性前列腺切除术后尿失禁管理中是否有效?
Urol Int. 2006;77(1):9-12. doi: 10.1159/000092927.
4
Nerve sparing open radical retropubic prostatectomy--does it have an impact on urinary continence?保留神经的开放性耻骨后根治性前列腺切除术——对尿失禁有影响吗?
J Urol. 2006 Jul;176(1):189-95. doi: 10.1016/S0022-5347(06)00574-X.
5
Urinary incontinence after radical prostatectomy: incidence by definition, risk factors and temporal trend in a large series with a long-term follow-up.根治性前列腺切除术后尿失禁:根据定义的发生率、危险因素及长期随访的大型队列研究中的时间趋势
BJU Int. 2006 Jun;97(6):1234-41. doi: 10.1111/j.1464-410X.2006.06185.x.
6
Preliminary results on the off-label use of duloxetine for the treatment of stress incontinence after radical prostatectomy or cystectomy.度洛西汀用于根治性前列腺切除术或膀胱切除术后压力性尿失禁的非标签使用的初步结果。
Eur Urol. 2006 Jun;49(6):1075-8. doi: 10.1016/j.eururo.2006.01.038. Epub 2006 Feb 6.
7
Comprehensive urodynamics evaluation of 146 men with incontinence after radical prostatectomy.对146例前列腺癌根治术后尿失禁男性患者进行全面尿动力学评估。
Urology. 2005 Aug;66(2):392-6. doi: 10.1016/j.urology.2005.03.026.
8
Pharmacotherapy for stress urinary incontinence.压力性尿失禁的药物治疗
Curr Opin Urol. 2005 Jul;15(4):227-30. doi: 10.1097/01.mou.0000172394.60481.47.
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Preliminary results of the effect of extracorporeal magnetic stimulation on urinary incontinence after radical prostatectomy: a pilot study.体外磁刺激对前列腺癌根治术后尿失禁影响的初步结果:一项前瞻性研究。
Urol Int. 2005;74(3):224-8. doi: 10.1159/000083553.
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Duloxetine: mechanism of action at the lower urinary tract and Onuf's nucleus.度洛西汀:在下尿路及奥努夫核的作用机制
Clin Auton Res. 2004 Aug;14(4):220-7. doi: 10.1007/s10286-004-0197-8.