Hatipoğlu Hasan, Keçeli Hüseyin Gencay, Güncü Güliz N, Sengün Dilek, Tözüm Tolga F
Dumlupinar University Research and Training Hospital, Kütahya, Turkey.
Clin Oral Investig. 2007 Jun;11(2):107-13. doi: 10.1007/s00784-006-0084-x. Epub 2007 Feb 9.
The shrinkage of free gingival grafts (FGGs) is a well-known clinical phenomenon but there are limited studies demonstrating the dimensional changes during healing in FGGs. The aim of the study is to examine the shrinkage of FGG in both horizontal and vertical dimensions and calculate the changes in the surface area of the graft at early and delayed periods of healing. The FGG procedure was applied to 15 consecutive patients in their mandibular anterior area. The graft sizes and areas were measured and the shrinkage of the graft was calculated at baseline and days 10, 21 and 180. Hemorrhage, sense alteration and pain symptoms were also examined. Change in the horizontal direction was not statistically significant during the whole study period (p > 0.05). However, there was a statistically significant reduction in the vertical direction in all visits, except day 10 (p < 0.05). Calculated graft area was also significantly reduced during the study period at all time-points compared to the baseline (p < 0.001). At day 10, 4 (26.7%) recipient sites and 5 (33%) donor sites demonstrated paresthesia. Only one (0.07%) recipient site demonstrated paresthesia at day 21 where the donor site resulted with an uneventful healing. At day 10, 5 (33%) patients demonstrated bleeding at their donor regions and resulted with a complete cessation of bleeding at day 21. Pain symptom was found in 8 (53.3%) recipient sites where 3 (20%) donor regions presented pain symptom at day 10. Graft shrinkage in the vertical dimension seems to affect the clinical outcomes of the FGG procedure. However, the influence of horizontal graft shrinkage was minimal.
游离龈瓣移植术（FGGs）的收缩是一种众所周知的临床现象，但仅有有限的研究证实了FGGs愈合过程中的尺寸变化。本研究的目的是检测FGG在水平和垂直维度上的收缩情况，并计算愈合早期和延迟期移植物表面积的变化。FGG手术应用于15例连续的下颌前部区域患者。测量移植物的大小和面积，并在基线、第10天、第21天和第180天计算移植物的收缩率。还检查了出血、感觉改变和疼痛症状。在整个研究期间，水平方向的变化无统计学意义（p>0.05）。然而，除第10天外，所有随访中垂直方向均有统计学意义的减小（p<0.05）。与基线相比，研究期间所有时间点计算的移植物面积也显著减小（p<0.001）。在第10天，4个（26.7%）受植区和5个（33%）供区出现感觉异常。在第21天，只有1个（0.07%）受植区出现感觉异常，供区愈合良好。在第10天，5例（33%）患者供区出血，在第21天出血完全停止。在第10天，8个（53.3%）受植区出现疼痛症状，3个（20%）供区出现疼痛症状。垂直维度的移植物收缩似乎影响FGG手术的临床效果。然而，水平移植物收缩的影响最小。
