Simonenko V B, Frank G A, Zavalishina L E, Makanin M A, Ostrovskaia E Iu, Beliaev L B, Dulin P A
Klin Med (Mosk). 2006;84(12):62-4.
Chronic lympholeucosis (CLL) is a B-cell lymphoproliferative disease, the morphological substrate of which is a clone of lymphocytes similar in size and morphology to normal mature lymphocyte and similar in immunophenotype to B lymphocytes at late stages of differentiation. The occurrence of large-cell lymphoma against the background of B-CLL is called Richter syndrome. A new tumor may occur in lymph nodes, the spleen, the liver, and the gastrointestinal tract (GIT). GIT involvement in Richter syndrome is a very rare case; the authors found only six descriptions of such cases in available literature, and no such description in Russian literature. The authors adduce their own observation.
