Feddersen R M, Smith A Y
Department of Pathology, University of New Mexico School of Medicine, albuquerque.
J Urol. 1992 Jan;147(1):118-9. doi: 10.1016/s0022-5347(17)37152-5.
Lymphomatoid granulomatosis is an angioinvasive proliferation of atypical T lymphocytes, with frequent pulmonary, cutaneous and neurological manifestations. Urological complications are infrequent. We describe the case of a 40-year-old man who presented with typical intrathoracic findings of lymphomatoid granulomatosis. Following a chemotherapy-induced remission he had retroperitoneal recurrence with bilateral ureteral obstruction, hydronephrosis and renal insufficiency. Histological examination revealed, in addition to the characteristic lymphoid infiltrates of lymphomatoid granulomatosis, a sclerosing process similar to idiopathic retroperitoneal fibrosis.
淋巴瘤样肉芽肿病是一种非典型T淋巴细胞的血管侵袭性增殖，常伴有肺部、皮肤和神经表现。泌尿系统并发症并不常见。我们报告一例40岁男性患者，其表现出淋巴瘤样肉芽肿病典型的胸腔内表现。化疗诱导缓解后，他出现腹膜后复发，伴有双侧输尿管梗阻、肾积水和肾功能不全。组织学检查显示，除了淋巴瘤样肉芽肿病特征性的淋巴浸润外，还有一个类似于特发性腹膜后纤维化的硬化过程。
