Buonavoglia Canio, Martella Vito
Department of Animal Health and Wellbeing, Faculty of Veterinary Medicine of Bari, Italy.
Vet Res. 2007 Mar-Apr;38(2):355-73. doi: 10.1051/vetres:2006058. Epub 2007 Feb 13.
Acute contagious respiratory disease (kennel cough) is commonly described in dogs worldwide. The disease appears to be multifactorial and a number of viral and bacterial pathogens have been reported as potential aetiological agents, including canine parainfluenza virus, canine adenovirus and Bordetella bronchiseptica, as well as mycoplasmas, Streptococcus equi subsp. zooepidemicus, canine herpesvirus and reovirus-1,-2 and -3. Enhancement of pathogenicity by multiple infections can result in more severe clinical forms. In addition, acute respiratory diseases associated with infection by influenza A virus, and group I and II coronaviruses, have been described recently in dogs. Host species shifts and tropism changes are likely responsible for the onset of these new pathogens. The importance of the viral agents in the kennel cough complex is discussed.
急性传染性呼吸道疾病（犬窝咳）在全球范围内的犬类中普遍存在。该疾病似乎是多因素导致的，据报道，多种病毒和细菌病原体可能是其病因，包括犬副流感病毒、犬腺病毒、支气管败血博德特氏菌，以及支原体、马链球菌兽疫亚种、犬疱疹病毒和呼肠孤病毒1型、2型和3型。多重感染增强致病性可导致更严重的临床症状。此外，最近在犬类中还发现了与甲型流感病毒以及I组和II组冠状病毒感染相关的急性呼吸道疾病。宿主物种转移和嗜性变化可能是这些新病原体出现的原因。本文讨论了病毒病原体在犬窝咳综合征中的重要性。
