Böddinghaus B K, Ludwig R J, Kaufmann R, Enzensberger R, Gies V, Kramme S, Brade V, Brandt C M
Institute of Medical Microbiology, University Hospital Frankfurt, Frankfurt/Main, Germany.
Infection. 2007 Feb;35(1):37-9. doi: 10.1007/s15010-006-5129-1.
Herein, we describe a case of leprosy in a 29-year-old pregnant southeast-asian woman who presented with joint pain and multiple disseminated erythematous macules, papules and plaques. Histological examination and stains for acid-fast bacilli from skin biopsies substantiated the clinical suspicion of a cutaneous mycobacterial disease and both should be performed in all patients with unidentified skin lesions. The definitive laboratory diagnosis of leprosy was achieved by the application of a species-specific real-time polymerase chain reaction from infected tissue.
在此,我们描述了一例29岁东南亚孕妇患麻风病的病例,该患者表现为关节疼痛以及多发的弥漫性红斑、丘疹和斑块。皮肤活检的组织学检查和抗酸杆菌染色证实了临床对皮肤分枝杆菌病的怀疑,所有不明皮肤病变患者均应进行这两项检查。通过对感染组织应用种特异性实时聚合酶链反应,实现了麻风病的确切实验室诊断。