Khalmatova B T
Zh Mikrobiol Epidemiol Immunobiol. 2006 Nov-Dec(7):97-9.
57 children with thymomegaly from 3 months to 3 years of age with acute lower respiratory tract infections were studied. Disturbances of gut microflora - changes in both obligate and potentially harmful symbionts were detected in 70.2% of cases. In 47,5% of cases increased quantity of enterococci was observed. Decreased quantities of bifidobacteria and lactobacilli were observed in all and 27.5% of studied patients respectively. Most diverse gut microflora has been observed in children with pneumonia and thymomegaly of II level. During treatment of children with thymomegaly changes in gut microflora should be considered along with changes in the immune system.
对57例年龄在3个月至3岁之间患有胸腺肿大并伴有急性下呼吸道感染的儿童进行了研究。在70.2%的病例中检测到肠道微生物群紊乱——专性共生菌和潜在有害共生菌均发生了变化。在47.5%的病例中观察到肠球菌数量增加。分别在所有研究患者和27.5%的研究患者中观察到双歧杆菌和乳酸杆菌数量减少。在患有肺炎和II级胸腺肿大的儿童中观察到最为多样的肠道微生物群。在治疗患有胸腺肿大的儿童时,应将肠道微生物群的变化与免疫系统的变化一并考虑。