Walsh S R, Gilson N L, Brown K, Novell J R
Department of General Surgery, Luton & Dunstable NHS Trust, Bedfordshire, UK.
Colorectal Dis. 2007 Mar;9(3):207-9. doi: 10.1111/j.1463-1318.2006.01105.x.
The 2-week rule has reduced waiting times for a specialist opinion among patients with a suspected malignancy. We aimed at assessing the effect of this rule on colorectal cancer survival.
Patients diagnosed with colorectal cancer before (group 1) and after (group 2) the introduction of the 2-week rule were identified from a prospective database. Emergency patients were excluded. Overall 2-year survival for each group was calculated using the Kaplan-Meier method and compared using the log-rank test.
Waiting times fell from 26 to 21 days (P =0.22). There was no significant difference in 2-year survival between the groups (hazard ratio 1.1; P = 0.56). There was a slight divergence between the survival curves at 2 years.
There has been no improvement in 2-year survival from colorectal cancer following the introduction of the 2-week rule.
“两周规则”缩短了疑似恶性肿瘤患者获得专科医生意见的等待时间。我们旨在评估该规则对结直肠癌生存率的影响。
从一个前瞻性数据库中识别出在引入“两周规则”之前（第1组）和之后（第2组）被诊断为结直肠癌的患者。排除急诊患者。使用Kaplan-Meier方法计算每组的总体2年生存率，并使用对数秩检验进行比较。
等待时间从26天降至21天（P = 0.22）。两组之间的2年生存率无显著差异（风险比1.1；P = 0.56）。2年时生存曲线略有差异。
引入“两周规则”后，结直肠癌的2年生存率没有提高。
