利用微电极阵列从猪硬脑膜下皮质表面记录的微场诱发电位。
Micro-field evoked potentials recorded from the porcine sub-dural cortical surface utilizing a microelectrode array.
作者信息
Kitzmiller Joseph P, Hansford Derek J, Fortin Linda D, Obrietan Karl H, Bergdall Valerie K, Beversdorf David Q
机构信息
Department of Neurology, The Ohio State University, Means Hall 469, 1654 Upham Drive, Columbus, OH 43210, USA.
出版信息
J Neurosci Methods. 2007 May 15;162(1-2):155-61. doi: 10.1016/j.jneumeth.2007.01.004. Epub 2007 Jan 13.
A sub-dural surface microelectrode array designed to detect micro-field evoked potentials has been developed. The device is comprised of an array of 350-microm square gold contacts, with bidirectional spacing of 150 microm, contained within a polyimide Kapton material. Cytotoxicity testing suggests that the device is suitable for use with animal and human patients. Implementation of the device in animal studies revealed that reliable evoked potentials could be acquired. Further work will be needed to determine how these micro-field potentials, which demonstrate selectivity for one eye, relate to the distribution of the ocular dominance columns of the occipital cortex.
一种用于检测微场诱发电位的硬膜下表面微电极阵列已被开发出来。该装置由350微米见方的金触点阵列组成，双向间距为150微米，封装在聚酰亚胺Kapton材料中。细胞毒性测试表明该装置适用于动物和人类患者。在动物研究中使用该装置发现可以获得可靠的诱发电位。还需要进一步的工作来确定这些对一只眼睛具有选择性的微场电位与枕叶皮质眼优势柱的分布之间的关系。
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