Friederich Hans-Christoph, Schild Sandra, Wild Beate, de Zwaan Martina, Quenter Andrea, Herzog Wolfgang, Zipfel Stephan
Department of Psychosomatic and General Internal Medicine, University of Heidelberg, Heidelberg, Germany.
Obesity (Silver Spring). 2007 Feb;15(2):283-7. doi: 10.1038/oby.2007.545.
There is a controversial discussion in the literature as to whether individuals with subthreshold binge eating disorder (subBED) differ clinically significantly from individuals with full-syndrome binge eating disorder (BED). This study was designed to compare eating-related and general psychopathology at baseline and in response to a multimodal treatment program in obese people with subBED compared with BED.
A total of 96 obese participants (BMI > or = 30 kg/m(2)) were assessed for eating-related and general psychopathology at baseline. Thirty-nine participants meeting criteria for BED and 19 participants meeting criteria for subBED attended a 15-session outpatient group therapy including cognitive behavioral therapy extended by interpersonal therapy, nutritional counseling, and a supervised walking exercise. Participants with eating disorders were reassessed at the end of treatment and at 3-month follow-up. The obese control group without an eating disorder (n = 38) was assessed once. This was not a randomized controlled trial.
Intent-to-treat analyses revealed no differences between subBED and full-syndrome BED participants with regard to eating-related and general psychopathology at baseline and with regard to treatment outcome. All participants experienced substantial improvements, and the results remained stable during follow-up (except for dietary restraint). At follow-up, participants with subBED and BED remained different from non-eating disorder controls in eating-related but not general psychopathology.
The findings indicate that our multimodal treatment program is equally effective in obese subBED and BED participants, suggesting that a differentiation currently seems not to be of clinical significance.
关于阈下暴食障碍(subBED)个体与完全综合征暴食障碍(BED)个体在临床上是否存在显著差异,文献中存在有争议的讨论。本研究旨在比较患有subBED的肥胖者与患有BED的肥胖者在基线时以及对多模式治疗方案的反应中的饮食相关和一般精神病理学情况。
共有96名肥胖参与者(BMI≥30kg/m²)在基线时接受了饮食相关和一般精神病理学评估。39名符合BED标准的参与者和19名符合subBED标准的参与者参加了为期15节的门诊团体治疗,包括认知行为疗法并扩展为人际疗法、营养咨询和有监督的步行锻炼。饮食失调的参与者在治疗结束时和3个月随访时再次接受评估。无饮食失调的肥胖对照组(n = 38)仅接受了一次评估。这不是一项随机对照试验。
意向性分析显示,subBED参与者与完全综合征BED参与者在基线时的饮食相关和一般精神病理学以及治疗结果方面没有差异。所有参与者都有显著改善,并且在随访期间结果保持稳定(除了饮食限制)。在随访时,患有subBED和BED的参与者在饮食相关精神病理学方面与无饮食失调对照组仍存在差异,但在一般精神病理学方面则没有差异。
研究结果表明,我们的多模式治疗方案对肥胖的subBED和BED参与者同样有效,这表明目前的区分似乎没有临床意义。