Matsumoto Naomi, Ikeda Manabu, Fukuhara Ryuji, Shinagawa Shunichiro, Ishikawa Tomohisa, Mori Takaaki, Toyota Yasutaka, Matsumoto Teruhisa, Adachi Hiroyoshi, Hirono Nobutsugu, Tanabe Hirotaka
Department of Neuropsychiatry, Neuroscience, Ehime University Graduate School of Medicine, Ehime, Japan.
Dement Geriatr Cogn Disord. 2007;23(4):219-24. doi: 10.1159/000099472. Epub 2007 Feb 9.
Despite many studies about the association between caregiver burden and behavioral and psychological symptoms of dementia (BPSD), there have been no population-based studies to evaluate caregiver burden associated with each BPSD.
To evaluate caregiver burden associated with the individual BPSD in elderly people living in the community.
The subjects were 67 participants with dementia living with their caregivers (diagnosed in the third Nakayama study): 51 Alzheimer's disease, 5 vascular dementia and 11 other. The Neuropsychiatric Inventory (NPI) and NPI Caregiver Distress Scale (NPI-D) were used to assess subjects' BPSD and related caregiver distress, respectively.
In the subjects exhibiting BPSD, aberrant motor behavior had the highest mean NPI score, and depression/dysphoria had the lowest. Agitation/aggression had the highest mean NPI-D score, and euphoria/elation had the lowest. Delusion, agitation/aggression, apathy/indifference, irritability/lability and aberrant motor behavior showed a correlation between the NPI and NPI-D scores.
The burden associated with BPSD is different for each symptom and does not always depend on frequency and severity of BPSD. These findings suggest that some symptoms, such as agitation/aggression and irritability/lability, may affect the caregivers significantly, although their frequency and severity are low.
尽管有许多关于照顾者负担与痴呆症行为和心理症状(BPSD)之间关联的研究,但尚未有基于人群的研究来评估与每种BPSD相关的照顾者负担。
评估社区居住老年人中与个体BPSD相关的照顾者负担。
研究对象为67名与照顾者共同生活的痴呆症患者(在第三次中山研究中被诊断):51例阿尔茨海默病,5例血管性痴呆和11例其他类型。分别使用神经精神科问卷(NPI)和NPI照顾者困扰量表(NPI-D)评估受试者的BPSD和相关照顾者困扰。
在表现出BPSD的受试者中,异常运动行为的平均NPI得分最高,而抑郁/烦躁得分最低。激越/攻击行为的平均NPI-D得分最高,而欣快/兴高采烈得分最低。妄想、激越/攻击行为、冷漠/漠不关心、易激惹/情绪不稳定和异常运动行为在NPI和NPI-D得分之间存在相关性。
与BPSD相关的负担因每种症状而异,并不总是取决于BPSD的频率和严重程度。这些发现表明,某些症状,如激越/攻击行为和易激惹/情绪不稳定,可能会对照顾者产生显著影响,尽管它们的频率和严重程度较低。