Chen Eunice Y, Brown Milton Z, Lo Tracy T Y, Linehan Marsha M
Department of Psychiatry, University of Chicago, Chicago, IL 60637, USA.
J Nerv Ment Dis. 2007 Feb;195(2):125-9. doi: 10.1097/01.nmd.0000254745.35582.f6.
We examined the rates of sexually transmitted diseases (STDs) in women with borderline personality disorder (BPD) (using PDE and SCID-II) and substance abuse or dependence (SCID-I) (BPD-SUD) (N=82) compared with those with BPD-only (N=102), exploring mediators of this relationship. Participants were interviewed about STD history (gonorrhea, genital herpes, syphilis, trichomonas, human papillomavirus, and HIV), condom use, number of sexual partners, poverty, and prostitution. BPD-SUD appeared to be particularly at high risk for STDs, reporting significantly more STDs than BPD (F[1,172]=11.74, p=0.001, d=.27), particularly for gonorrhea, trichomonas, and human papillomavirus. The relationship between BPD-SUD and STDs is mediated by poverty, prostitution in the last year, recent unprotected sex with two or more partners, and >20 lifetime partners (z=-2.16 which is p=0.03), with prostitution alone making a significant contribution to this relationship (z=-2.49, p=0.01).
我们研究了边缘性人格障碍（BPD）（使用精神疾病诊断与统计手册第四版轴Ⅱ人格障碍定式临床检查问卷[PDE]和精神疾病诊断与统计手册第二版[SCID-II]）合并物质滥用或依赖（使用精神疾病诊断与统计手册第一版[SCID-I]）（BPD-SUD）的女性（N = 82）与仅患有BPD的女性（N = 102）的性传播疾病（STD）发病率，并探讨了这种关系的中介因素。研究人员就STD病史（淋病、生殖器疱疹、梅毒、滴虫、人乳头瘤病毒和艾滋病毒）、避孕套使用情况、性伴侣数量、贫困状况和卖淫情况对参与者进行了访谈。BPD-SUD似乎特别容易感染STD，报告的STD病例明显多于BPD患者（F[1,172] = 11.74，p = 0.001，d = 0.27），尤其是淋病、滴虫和人乳头瘤病毒。BPD-SUD与STD之间的关系由贫困、过去一年中的卖淫行为、近期与两个或更多伴侣发生无保护性行为以及一生中有超过20个性伴侣所介导（z = -2.16，p = 0.03），仅卖淫行为就对这种关系有显著影响（z = -2.49，p = 0.01）。
