Waring W P, McLaurin T M
Department of Physical Medical and Rehabilitation, University of Michigan, Ann Arbor.
Arch Phys Med Rehabil. 1992 Jan;73(1):37-9.
Measurements of stride length, gait speed, and distance walked during seven days were obtained from 15 postpolio and eight control subjects. Pedometers were used to measure distance walked. Measurements of stride length and speed were performed three times, and there was a high correlation between tests (R = .852-.969). The pedometers failed to record accurately in some postpolio subjects, and these subjects were dropped from analysis when ambulation distance was used as a variable. There were significant differences between the postpolio subjects and controls with respect to gait speed (47.7 +/- 14.0 vs 74.9 +/- 15.9m/min, p less than 0.0005), stride length (55.3 +/- 11.7 vs 69.8 +/- 8.6cm, p = .006), and average kilometers walked per day for seven days (1.97 +/- 1.3 vs 3.89 +/- 1.7, p = .016). The postpolio subjects had their serum creatine kinase (CK) levels measured at the end of the study. Forty percent of subjects had a level above the normal limits of our laboratory. There was a significantly positive correlation between CK levels and the distance walked during the previous 24 hours (R = .75, p = .012). The findings of this study illustrate the impact of gait abnormalities on the ambulatory abilities of the postpolio population. The correlation of CK with ambulation supports the association of exercise as a source of elevated CK levels in the postpolio population.
我们从15名小儿麻痹后遗症患者和8名对照受试者那里获取了七天内的步幅、步态速度和行走距离的测量数据。使用计步器来测量行走距离。步幅和速度的测量进行了三次，测试之间具有高度相关性（R = 0.852 - 0.969）。在一些小儿麻痹后遗症患者中，计步器记录不准确，当将行走距离用作变量时，这些受试者被排除在分析之外。小儿麻痹后遗症患者和对照受试者在步态速度（47.7±14.0对74.9±15.9米/分钟，p＜0.0005）、步幅（55.3±11.7对69.8±8.6厘米，p = 0.006）以及七天内平均每天行走的公里数（1.97±1.3对3.89±1.7，p = 0.016）方面存在显著差异。在研究结束时，对小儿麻痹后遗症患者的血清肌酸激酶（CK）水平进行了测量。40%的受试者的水平高于我们实验室的正常范围。CK水平与前24小时行走的距离之间存在显著正相关（R = 0.75，p = 0.012）。本研究的结果说明了步态异常对小儿麻痹后遗症患者群体行走能力的影响。CK与行走之间的相关性支持了运动作为小儿麻痹后遗症患者群体中CK水平升高来源的关联。
