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[健康与病理状态下人和大鼠血液中红细胞电泳迁移率对细胞体积的依赖性]

[Dependence of erythrocyte electrophoretic mobility of human and rat blood on cell volume in health and pathology].

作者信息

Matiushichev V B, Shamratova V G

出版信息

Patol Fiziol Eksp Ter. 2006 Oct-Dec(4):17-8.

PMID:17300083
Abstract

To study correlations between electrophoretic mobility of erythrocytes and their volume, we compared blood samples from intact rats, animals exposed to extreme impacts, healthy humans and cancer patients. In rats, the above erythrocytes indices were closely related polynomially--deviations of the cell volume in both directions from physiological values are accompanied with a fall of mean cell mobility in electric field. In healthy subjects electrophoretic mobility of erythrocytes and their volume vary independently, in cancer these parameters are related curvilinearly.

摘要

为研究红细胞电泳迁移率与其体积之间的相关性,我们比较了来自完整大鼠、遭受极端冲击的动物、健康人类和癌症患者的血样。在大鼠中,上述红细胞指标呈多项式密切相关——细胞体积在两个方向上偏离生理值均伴随着电场中平均细胞迁移率的下降。在健康受试者中,红细胞的电泳迁移率及其体积独立变化,而在癌症患者中,这些参数呈曲线相关。

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