Leishmanial proteins can correct human mitochondrial mutations.

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作者信息

Lohia Anuradha

机构信息

Department of Biochemistry, Bose Institute, Kolkata 700 054, India.

出版信息

J Biosci. 2006 Dec;31(5):507-8. doi: 10.1007/BF02708400.

DOI:10.1007/BF02708400

PMID:17301486

Abstract

摘要

相似文献

Leishmanial proteins can correct human mitochondrial mutations.

J Biosci. 2006 Dec;31(5):507-8. doi: 10.1007/BF02708400.

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Treatment of human cells derived from MERRF syndrome by peptide-mediated mitochondrial delivery.通过肽介导的线粒体递送来治疗源自 MERRF 综合征的人类细胞。

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本文引用的文献

Functional delivery of a cytosolic tRNA into mutant mitochondria of human cells.将胞质转运RNA功能性递送至人类细胞的突变线粒体中。

Science. 2006 Oct 20;314(5798):471-4. doi: 10.1126/science.1129754.

Hum Mol Genet. 2004 Oct 15;13(20):2519-34. doi: 10.1093/hmg/ddh267. Epub 2004 Aug 18.

Allosteric regulation of tRNA import: interactions between tRNA domains at the inner membrane of Leishmania mitochondria.转运RNA导入的变构调节：利什曼原虫线粒体内膜上转运RNA结构域之间的相互作用

Nucleic Acids Res. 2003 Oct 1;31(19):5552-9. doi: 10.1093/nar/gkg773.

In vitro analysis of mutations causing myoclonus epilepsy with ragged-red fibers in the mitochondrial tRNA(Lys)gene: two genotypes produce similar phenotypes.线粒体tRNA（Lys）基因中导致肌阵挛性癫痫伴破碎红纤维的突变的体外分析：两种基因型产生相似的表型。

Mol Cell Biol. 1995 May;15(5):2872-81. doi: 10.1128/MCB.15.5.2872.

Mitochondrial diseases: gene mapping and gene therapy.

Cell. 1990 Jun 15;61(6):925-6. doi: 10.1016/0092-8674(90)90055-j.

Myoclonic epilepsy and ragged-red fiber disease (MERRF) is associated with a mitochondrial DNA tRNA(Lys) mutation.肌阵挛性癫痫伴蓬毛样红纤维病（MERRF）与线粒体DNA 赖氨酸转运RNA（tRNA<sup>Lys</sup>）突变有关。

Cell. 1990 Jun 15;61(6):931-7. doi: 10.1016/0092-8674(90)90059-n.

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