大砗磲化学自养共生菌基因组
The Calyptogena magnifica chemoautotrophic symbiont genome.
作者信息
Newton I L G, Woyke T, Auchtung T A, Dilly G F, Dutton R J, Fisher M C, Fontanez K M, Lau E, Stewart F J, Richardson P M, Barry K W, Saunders E, Detter J C, Wu D, Eisen J A, Cavanaugh C M
机构信息
Harvard University, 16 Divinity Avenue, Biolabs 4080, Cambridge, MA 02138, USA.
出版信息
Science. 2007 Feb 16;315(5814):998-1000. doi: 10.1126/science.1138438.
Chemoautotrophic endosymbionts are the metabolic cornerstone of hydrothermal vent communities, providing invertebrate hosts with nearly all of their nutrition. The Calyptogena magnifica (Bivalvia: Vesicomyidae) symbiont, Candidatus Ruthia magnifica, is the first intracellular sulfur-oxidizing endosymbiont to have its genome sequenced, revealing a suite of metabolic capabilities. The genome encodes major chemoautotrophic pathways as well as pathways for biosynthesis of vitamins, cofactors, and all 20 amino acids required by the clam.
化能自养内共生体是热液喷口群落的代谢基石，为无脊椎动物宿主提供几乎所有营养。巨大潜泥蛤（双壳纲：泥蛤科）的共生体，即“壮丽露丝菌”，是首个基因组被测序的细胞内硫氧化内共生体，揭示了一系列代谢能力。该基因组编码主要的化能自养途径以及维生素、辅因子和蛤蜊所需的全部20种氨基酸的生物合成途径。
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