Unni Harikrishnan N, Keh Huan J, Yang Chun
School of Mechanical and Aerospace Engineering, Nanyang Technological University, Singapore.
Electrophoresis. 2007 Feb;28(4):658-64. doi: 10.1002/elps.200600576.
Electrokinetically driven microfluidic devices that are used for biological cell/particle manipulation (e.g., cell sorting, separation) involve electrokinetic transport of these particles in microchannels whose dimension is comparable with particles' size. This paper presents an analytical study on electrokinetic transport of a charged spherical particle in a charged parallel-plate microchannel. Under the thin electric double-layer assumption, solutions in closed-form solutions for the particle velocity and disturbed electrical and fluid velocity fields are obtained for plane-symmetric (along the channel centerline) and asymmetric (off the channel centerline) motions of a sphere in a parallel-plate microchannel. The effects of relative particle size and eccentricity (i.e., off the centerline distance) on a particle's translational and rotational velocities are analyzed.
用于生物细胞/颗粒操纵（如细胞分选、分离）的电动驱动微流控装置涉及这些颗粒在尺寸与颗粒大小相当的微通道中的电动输运。本文对带电平行板微通道中带电球形颗粒的电动输运进行了分析研究。在薄电双层假设下，针对平行板微通道中球体的平面对称（沿通道中心线）和非对称（偏离通道中心线）运动，得到了颗粒速度以及扰动电场和流体速度场的封闭形式解。分析了相对颗粒尺寸和偏心率（即偏离中心线的距离）对颗粒平移和旋转速度的影响。
