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一名帕金森病患者合并有含杆状体的肌病伴弯腰驼背。

Camptocormia in a patient with Parkinson disease and a myopathy with nemaline rods.

作者信息

Ozer Feriha, Ozturk Oya, Meral Hasan, Serdaroglu Piraye, Yayla Vildan

机构信息

Department of Neurology, Haseki Educational and Research Hospital, Istanbul, Turkey.

出版信息

Am J Phys Med Rehabil. 2007 Jan;86(1):3-6. doi: 10.1097/phm.0b013e31802b8bde.

Abstract

Camptocormia, also referred to as bent spine, is a gait disorder characterized by hyperflexion of the thoracolumbar spine that develops in recumbent position while walking and that disappears in supine position. Myopathy is one of the frequent causes of camptocormia. A 77-yr-old male patient who was followed up with the diagnosis of rheumatoid arthritis for 2 yrs was admitted with progressive gait deterioration. Hyperflexion of trunk, disappearing in supine position, was detected and diagnosed as camptocormia. He also exhibited the signs of parkinsonism. A paraspinal muscle biopsy showed myopathy with rods in many muscle fibers. Camptocormia in this patient may be attributable to the myopathic weakness of thoracolumbar paraspinal muscles. The normal biceps brachii muscle biopsy refers to the isolated affection of paraspinal muscles in this patient. A camptocormia (bent spine) case of myopathy with nemaline rods associated with Parkinson disease is presented.

摘要

弯腰驼背症,也称为脊柱弯曲,是一种步态障碍,其特征为胸腰椎过度前屈,在行走时呈俯卧位出现,仰卧位时消失。肌病是弯腰驼背症的常见病因之一。一名77岁男性患者,因类风湿性关节炎诊断随访2年,因进行性步态恶化入院。发现躯干过度前屈,仰卧位时消失,诊断为弯腰驼背症。他还表现出帕金森综合征的体征。椎旁肌活检显示许多肌纤维中有杆状体的肌病。该患者的弯腰驼背症可能归因于胸腰椎椎旁肌的肌病性无力。肱二头肌活检正常表明该患者仅椎旁肌受累。本文报告一例伴有杆状体的肌病性弯腰驼背症(脊柱弯曲)病例,该病例与帕金森病相关。

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