Novel malonamide derivatives as potent kappa opioid receptor agonists.

作者信息

Chu Guo-Hua, Gu Minghua, Cassel Joel A, Belanger Serge, Graczyk Thomas M, DeHaven Robert N, Conway-James Nathalie, Koblish Michael, Little Patrick J, DeHaven-Hudkins Diane L, Dolle Roland E

机构信息

Department of Chemistry, Adolor Corporation, 700 Pennsylvania Drive, Exton, PA 19341, USA.

出版信息

Bioorg Med Chem Lett. 2007 Apr 1;17(7):1951-5. doi: 10.1016/j.bmcl.2007.01.053. Epub 2007 Jan 25.

DOI:10.1016/j.bmcl.2007.01.053

PMID:17307360

Abstract

A novel series of malonamide derivatives was synthesized. These amides were shown to be potent and selective kappa opioid receptor agonists.

摘要

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