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眼镜王蛇:两例亚洲眼镜蛇咬伤中毒病例

Naja Kaouthia: two cases of Asiatic cobra envenomations.

作者信息

Khandelwal Gautam, Katz Kenneth D, Brooks Daniel E, Gonzalez Stephanie M, Ulishney Colleen D

机构信息

Department of Emergency Medicine, University of Pittsburgh Medical Center, Presbyterian Hospital, Pittsburgh, Pennsylvania 15213, USA.

出版信息

J Emerg Med. 2007 Feb;32(2):171-4. doi: 10.1016/j.jemermed.2006.05.047. Epub 2007 Jan 17.

Abstract

Envenomation from cobra bites causes major morbidity and mortality in Asia and Africa but rarely in the United States. We describe two patients bitten by the Asiatic Cobra (Naja Kaouthia)--both successfully treated in the emergency department. Patient 1 was a 23-year-old woman bitten in the buttock by her cobra. Examination demonstrated two puncture wounds. She developed cranial neuropathy, respiratory failure, and coagulopathy 10 h later, necessitating endotracheal intubation and polyvalent antivenom administration. The patient recovered fully with minimal wound necrosis. Patient 2, a 44-year-old man, was bitten on the hand by his cobra. Examination revealed a puncture wound with progressive swelling. Edrophonium and monovalent antivenom were administered, and he recovered uneventfully. These cases emphasize the varied clinical presentations of the Asiatic cobra. Patient 1 developed delayed neurotoxicity, respiratory failure, and hematotoxicity with minimal wound necrosis, whereas Patient 2 experienced a more typical clinical course.

摘要

眼镜蛇咬伤所致的中毒在亚洲和非洲会导致严重的发病和死亡情况,但在美国却很少见。我们描述了两名被亚洲眼镜蛇(眼镜王蛇)咬伤的患者——两人均在急诊科成功接受治疗。患者1是一名23岁女性,被自家的眼镜蛇咬伤臀部。检查发现有两处穿刺伤。10小时后,她出现了颅神经病变、呼吸衰竭和凝血病,需要进行气管插管并注射多价抗蛇毒血清。患者伤口坏死轻微,完全康复。患者2是一名44岁男性,被自家的眼镜蛇咬伤手部。检查发现有一处穿刺伤,伴有逐渐加重的肿胀。给予了依酚氯铵和单价抗蛇毒血清,他顺利康复。这些病例强调了亚洲眼镜蛇临床表现的多样性。患者1出现了延迟性神经毒性、呼吸衰竭和血液毒性,伤口坏死轻微,而患者2经历了更典型的临床病程。

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