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2004年肯尼亚急性黄曲霉毒素中毒事件:致病因子的鉴定

Outbreak of an acute aflatoxicosis in Kenya in 2004: identification of the causal agent.

作者信息

Probst Claudia, Njapau Henry, Cotty Peter J

机构信息

University of Arizona, USDA-ARS, Department of Plant Sciences, Tucson, AZ 85721, USA.

出版信息

Appl Environ Microbiol. 2007 Apr;73(8):2762-4. doi: 10.1128/AEM.02370-06. Epub 2007 Feb 16.

Abstract

Maize contaminated with aflatoxins has been implicated in deadly epidemics in Kenya three times since 1981, but the fungi contaminating the maize with aflatoxins have not been characterized. Here we associate the S strain of Aspergillus flavus with lethal aflatoxicoses that took more than 125 lives in 2004.

摘要

自1981年以来,受黄曲霉毒素污染的玉米已在肯尼亚引发了三次致命疫情,但污染玉米的黄曲霉毒素的真菌尚未得到鉴定。在这里,我们将黄曲霉的S菌株与2004年导致125人死亡的致命黄曲霉毒素中毒事件联系起来。

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本文引用的文献

1
Living Maize Embryo Influences Accumulation of Aflatoxin in Maize Kernels.
J Food Prot. 1993 Nov;56(11):967-971. doi: 10.4315/0362-028X-56.11.967.
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Case-control study of an acute aflatoxicosis outbreak, Kenya, 2004.
Environ Health Perspect. 2005 Dec;113(12):1779-83. doi: 10.1289/ehp.8384.
10
Aflatoxin biosynthesis gene clusters and flanking regions.
J Appl Microbiol. 2005;99(3):518-27. doi: 10.1111/j.1365-2672.2005.02637.x.

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