Cerynik Douglas L, Lee Gwo-Chin, Fayssoux Reginald, Amin Nirav H
Department of Orthopaedic Surgery, Hahnemann University Hospital, Philadelphia, PA 19102, USA.
Clin Orthop Relat Res. 2007 Jun;459:260-2. doi: 10.1097/BLO.0b013e31803d3aad.
Antibiotic-induced hemolytic anemia is a rare complication. Prophylactic cephalosporins are widely used in patients having orthopaedic procedures. When there is a precipitous drop in hemoglobin levels, it is important for the clinician to consider the possibility of drug-induced anemia when other causes of blood loss have been excluded. We present a patient with no prior drug allergies who had antibiotic-induced hemolytic anemia develop after total knee arthroplasty.
抗生素诱发的溶血性贫血是一种罕见的并发症。预防性头孢菌素广泛应用于接受骨科手术的患者。当血红蛋白水平急剧下降时，在排除其他失血原因后，临床医生考虑药物性贫血的可能性很重要。我们报告一例既往无药物过敏史的患者，在全膝关节置换术后发生了抗生素诱发的溶血性贫血。
