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丙型肝炎-血吸虫病合并感染中细胞因子的初步评估。

Preliminar evaluation of cytokines in the hepatitis C-schistosomiasis co-infection.

作者信息

Morais Clarice N L, Carvalho Bruno M, Melo Wlademir G, Lopes Edmundo P A, Domingues Ana Lúcia C, Jucá Norma T, Souza Wayner, Abath Frederico G C, Montenegro Silvia M L

机构信息

Centro de Pesquisas Aggeu Magalhães-Fiocruz, Av. Prof. Moraes Rego, 52020-020 Recife, PE, Brazil.

出版信息

Mem Inst Oswaldo Cruz. 2006 Sep;101 Suppl 1:353-4. doi: 10.1590/s0074-02762006000900057.

DOI:10.1590/s0074-02762006000900057
PMID:17308796
Abstract

Evaluation of hepatic fibrosis is usually performed by histopathological examination of biopsies. However, this is an invasive and potentially dangerous procedure. Several studies have proposed serum biological markers of hepatic fibrosis. This communication evaluates the use of serum cytokines as markers of hepatic fibrosis in hepatitis C, schistosomiasis, and co-infection.

摘要

肝纤维化的评估通常通过活检的组织病理学检查来进行。然而,这是一种侵入性且有潜在危险的操作。多项研究提出了肝纤维化的血清生物学标志物。本报告评估了血清细胞因子作为丙型肝炎、血吸虫病及合并感染中肝纤维化标志物的用途。

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Preliminar evaluation of cytokines in the hepatitis C-schistosomiasis co-infection.丙型肝炎-血吸虫病合并感染中细胞因子的初步评估。
Mem Inst Oswaldo Cruz. 2006 Sep;101 Suppl 1:353-4. doi: 10.1590/s0074-02762006000900057.
2
Progression of fibrosis in hepatitis C with and without schistosomiasis: correlation with serum markers of fibrosis.合并及未合并血吸虫病的丙型肝炎患者纤维化的进展:与纤维化血清标志物的相关性
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引用本文的文献

1
Gene profile of chemokines on hepatic stellate cells of schistosome-infected mice and antifibrotic roles of CXCL9/10 on liver non-parenchymal cells.肝星状细胞中感染血吸虫小鼠趋化因子的基因谱及 CXCL9/10 对肝非实质细胞的抗纤维化作用。
PLoS One. 2012;7(8):e42490. doi: 10.1371/journal.pone.0042490. Epub 2012 Aug 8.
2
Schistosomiasis mansoni: ultrasound-evaluated hepatic fibrosis and serum concentrations of hyaluronic acid.曼氏血吸虫病:超声评估的肝纤维化及血清透明质酸浓度
Ann Trop Med Parasitol. 2011 Apr;105(3):233-9. doi: 10.1179/136485911X12987676649629.
3
The signaling function of the IL-13Ralpha2 receptor in the development of gastrointestinal fibrosis and cancer surveillance.
白细胞介素-13受体α2(IL-13Rα2)受体在胃肠道纤维化发展和癌症监测中的信号传导功能。
Curr Mol Med. 2009 Aug;9(6):740-50. doi: 10.2174/156652409788970652.