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来自漆姑草(石竹科)的环肽。

Cyclopeptides from Sagina japonica (Caryophyllaceae).

作者信息

Jia Ai-qun, Tan Ning-hua, Zhou Jun

机构信息

Bioengineering Laboratory, Nanjing University of Science and Technology, Nanjing, Jiangsu, PR China.

出版信息

Chem Biodivers. 2007 Feb;4(2):241-7. doi: 10.1002/cbdv.200790029.

Abstract

Two new cyclic peptides, named sajaponicin C (1) and sajaponicin D (2), were isolated from the whole plants of Sagina japonica (Caryophyllaceae). Their structures were determined as cyclo(Pro(2)-Leu(2)-Tyr-Leu(1)-Phe(1)-Pro(3)-Phe(2)-Pro(1)) (1) and cyclo(Pro(1)-Pro(2)-Pro(3)-Pro(4)-Phe(1)-Gly-Thr-Ser-Phe(2)-Ile-Tyr) (2) on the basis of spectroscopic data, especially by two-dimensional (2D) NMR techniques.

摘要

从漆姑草(石竹科)的全草中分离出两种新的环肽,命名为漆姑草素C(1)和漆姑草素D(2)。基于光谱数据,特别是二维(2D)核磁共振技术,确定它们的结构分别为环(脯氨酸(2)-亮氨酸(2)-酪氨酸-亮氨酸(1)-苯丙氨酸(1)-脯氨酸(3)-苯丙氨酸(2)-脯氨酸(1))(1)和环(脯氨酸(1)-脯氨酸(2)-脯氨酸(3)-脯氨酸(4)-苯丙氨酸(1)-甘氨酸-苏氨酸-丝氨酸-苯丙氨酸(2)-异亮氨酸-酪氨酸)(2)。

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