Lee K C, Tami T A, Lalwani A K, Schecter G
Department of Otolaryngology, San Francisco General Hospital, University of California 94110.
Laryngoscope. 1992 Jan;102(1):60-4. doi: 10.1288/00005537-199201000-00012.
Although excisional biopsy has traditionally been required to diagnose cervical tuberculosis (TB), fine needle aspiration biopsy (FNAB) has also been found to be useful. The presentation and management of 47 patients diagnosed with cervical TB between 1984 and 1988 were retrospectively reviewed. Chest x-rays were normal in 58% of the patients, and purified protein derivative (PPD) skin testing was positive in 96%. When FNAB was used, TB could be suspected in 83% of cases and definitively established in 62%. Open biopsy correctly diagnosed cervical TB in all masses excised. Medical therapy alone resulted in resolution of disease in 94% of patients diagnosed by FNAB, and subsequent excisional biopsy was necessary in only one patient. The results suggest that FNAB is a useful initial procedure in the diagnosis of cervical TB. Excisional biopsy should be reserved for cases where no diagnosis by FNAB can be made, or for persistent cervical disease despite full-course antituberculous chemotherapy.
尽管传统上需要通过切除活检来诊断宫颈结核(TB),但细针穿刺活检(FNAB)也被证明是有用的。对1984年至1988年间诊断为宫颈结核的47例患者的临床表现和治疗情况进行了回顾性研究。58%的患者胸部X光片正常,96%的患者结核菌素纯蛋白衍生物(PPD)皮肤试验呈阳性。使用FNAB时,83%的病例可怀疑为结核,62%的病例可明确诊断。开放性活检对所有切除的肿块均正确诊断为宫颈结核。仅药物治疗使94%经FNAB诊断的患者病情得到缓解,仅1例患者需要随后进行切除活检。结果表明,FNAB是诊断宫颈结核的一种有用的初始检查方法。切除活检应保留用于无法通过FNAB做出诊断的病例,或用于尽管进行了全程抗结核化疗但宫颈疾病仍持续存在的病例。