Cheung W L, Siu K F, Ng A
Department of Surgery, University of Hong Kong, Queen Mary Hospital.
J R Coll Surg Edinb. 1990 Oct;35(5):293-5.
A prospective study was undertaken to determine the effectiveness of a 6-month four-drug regimen in the treatment of 123 patients with cervical tuberculous lymphadenitis. The results showed that the disease was satisfactorily controlled with residual lymph nodes which did not necessitate further chemotherapy in 14.6% of patients at 3 years follow-up. Recurrence requiring further chemotherapy occurred in 3.3% of patients between 9 and 28 months. Wound sinuses occurred in 3.3% of patients and all healed with conservative treatment. The culture results and numbers of lymph nodes at presentation had no effect on outcome at 3 years. An excisional procedure was associated with a lower incidence of residual lymph nodes than an incisional biopsy. Minor gastrointestinal upset from drug treatment was common, but only 2.4% of patients needed a change of regimen. Six months of combination chemotherapy is adequate for the treatment of the disease.
一项前瞻性研究旨在确定一种为期6个月的四联药物疗法对123例颈部结核性淋巴结炎患者的治疗效果。结果显示，在3年的随访中，14.6%的患者病情得到满意控制，残留淋巴结无需进一步化疗。9至28个月期间，3.3%的患者复发需要进一步化疗。3.3%的患者出现伤口窦道，经保守治疗均愈合。初诊时的培养结果和淋巴结数量对3年的治疗结果没有影响。与切开活检相比，切除手术残留淋巴结的发生率较低。药物治疗引起的轻微胃肠道不适很常见，但只有2.4%的患者需要更换治疗方案。六个月的联合化疗足以治疗该疾病。
