Kottwitz Jack J, Luis-Fuentes Virginia, Micheal Bindu
Department of Veterinary Clinical Sciences, The Ohio State University, College of Veterinary Medicine, 601 Vernon L. Tharpe Street, Columbus, Ohio 43210, USA.
J Zoo Wildl Med. 2006 Jun;37(2):197-201. doi: 10.1638/04-083.1.
A 4-yr-old male ferret (Mustela putorius furo) was presented with a 3-day history of pelvic limb ataxia and weakness. A cellulitis associated with a deep bite wound was identified and initially treated with antibiotics and anti-inflammatory medication. Two weeks later, a grade IV/VI cardiac murmur was identified on physical examination. Echocardiographic examination revealed irregular thickening of the aortic valve leaflets, with normal chamber dimensions and normal systolic function. The ferret's physical condition rapidly deteriorated and it was subsequently euthanatized. Myxomatous degeneration of the aortic valve leaflets, with ulceration and vegetative lesions, and multiorgan infarctions were identified during necropsy. A bacterial etiologic agent was not identified from blood culture or histopathology. Lesions present were consistent with nonbacterial thrombotic endocarditis, a novel condition in the ferret.
一只4岁雄性雪貂（鼬属欧洲雪貂）出现盆腔肢体共济失调和无力的症状已有3天。发现一处与深部咬伤伤口相关的蜂窝织炎，最初用抗生素和抗炎药物进行治疗。两周后，体格检查发现有IV/VI级心脏杂音。超声心动图检查显示主动脉瓣叶不规则增厚，心腔大小正常，收缩功能正常。雪貂的身体状况迅速恶化，随后实施了安乐死。尸检发现主动脉瓣叶黏液瘤样变性、溃疡和赘生物病变以及多器官梗死。血液培养或组织病理学检查均未发现细菌病原体。所呈现的病变与非细菌性血栓性心内膜炎相符，这在雪貂中是一种新情况。
