• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

New C-3' hydroxamate-substituted and more lipophilic cyclic hydroxamate cephalosporin derivatives as a potential new generation of selective antimicrobial agents.

作者信息

Miller Marvin J, Zhao Gaiying, Vakulenko Sergei, Franzblau Scott, Möllmann Ute

机构信息

Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, IN 46556, USA.

出版信息

Org Biomol Chem. 2006 Nov 21;4(22):4178-85. doi: 10.1039/b612475e.

DOI:10.1039/b612475e
PMID:17312974
Abstract
摘要

相似文献

1
New C-3' hydroxamate-substituted and more lipophilic cyclic hydroxamate cephalosporin derivatives as a potential new generation of selective antimicrobial agents.新型C-3'异羟肟酸酯取代且更具亲脂性的环状异羟肟酸酯头孢菌素衍生物作为新一代潜在的选择性抗菌剂。
Org Biomol Chem. 2006 Nov 21;4(22):4178-85. doi: 10.1039/b612475e.
2
New broad-spectrum parenteral cephalosporins exhibiting potent activity against both methicillin-resistant Staphylococcus aureus (MRSA) and Pseudomonas aeruginosa. Part 2: Synthesis and structure-activity relationships in the S-3578 series.新型广谱肠胃外注射用头孢菌素对耐甲氧西林金黄色葡萄球菌(MRSA)和铜绿假单胞菌均表现出强效活性。第2部分:S-3578系列的合成及构效关系
Bioorg Med Chem. 2004 Aug 1;12(15):4211-9. doi: 10.1016/j.bmc.2004.05.022.
3
New N-substituted 7-aminocephalosporanic acid derivatives as potential agents against Streptococcus pneumoniae. Synthesis and in vitro activity.新型N-取代7-氨基头孢烷酸衍生物作为抗肺炎链球菌的潜在药物。合成与体外活性
Bioorg Med Chem Lett. 1999 Apr 5;9(7):1035-40. doi: 10.1016/s0960-894x(99)00127-4.
4
Synthesis, antimicrobial and antiviral evaluation of substituted imidazole derivatives.取代咪唑衍生物的合成、抗菌及抗病毒活性评估
Eur J Med Chem. 2009 Jun;44(6):2347-53. doi: 10.1016/j.ejmech.2008.08.010. Epub 2008 Sep 11.
5
Antimicrobial activity of licorice flavonoids against methicillin-resistant Staphylococcus aureus.甘草黄酮对耐甲氧西林金黄色葡萄球菌的抗菌活性。
Fitoterapia. 2002 Oct;73(6):536-9. doi: 10.1016/s0367-326x(02)00168-5.
6
Studies on synthesis of novel pyrido[2,3-d]pyrimidine derivatives, evaluation of their antimicrobial activity and molecular docking.新型吡啶并[2,3 - d]嘧啶衍生物的合成、抗菌活性评估及分子对接研究
Bioorg Med Chem Lett. 2018 May 15;28(9):1670-1675. doi: 10.1016/j.bmcl.2018.03.022. Epub 2018 Mar 10.
7
S-3578, a new broad spectrum parenteral cephalosporin exhibiting potent activity against both methicillin-resistant Staphylococcus aureus (MRSA) and Pseudomonas aeruginosa. Synthesis and structure-activity relationships.S-3578,一种新型广谱肠胃外注射用头孢菌素,对耐甲氧西林金黄色葡萄球菌(MRSA)和铜绿假单胞菌均表现出强效活性。合成及构效关系。
J Antibiot (Tokyo). 2002 Nov;55(11):975-92. doi: 10.7164/antibiotics.55.975.
8
New broad-spectrum parenteral cephalosporins exhibiting potent activity against both methicillin-resistant Staphylococcus aureus (MRSA) and Pseudomonas aeruginosa. Part 3: 7beta-[2-(5-Amino-1,2,4-thiadiazol-3-yl)-2-ethoxyiminoacetamido] cephalosporins bearing 4-[3-(aminoalkyl)-ureido]-1-pyridinium at C-3'.对耐甲氧西林金黄色葡萄球菌(MRSA)和铜绿假单胞菌均表现出强效活性的新型广谱肠胃外头孢菌素。第3部分:在C-3'位带有4-[3-(氨基烷基)-脲基]-1-吡啶鎓的7β-[2-(5-氨基-1,2,4-噻二唑-3-基)-2-乙氧基亚氨基乙酰胺基]头孢菌素
Bioorg Med Chem. 2004 Aug 1;12(15):4221-31. doi: 10.1016/j.bmc.2004.05.021.
9
Ala-geninthiocin, a new broad spectrum thiopeptide antibiotic, produced by a marine Streptomyces sp. ICN19.阿来环素,一种由海洋链霉菌 ICN19 产生的新型广谱噻肽抗生素。
J Antibiot (Tokyo). 2019 Feb;72(2):99-105. doi: 10.1038/s41429-018-0115-2. Epub 2018 Oct 24.
10
Identification of novel 2-aminothiazole conjugated nitrofuran as antitubercular and antibacterial agents.新型2-氨基噻唑共轭硝基呋喃作为抗结核和抗菌剂的鉴定
Bioorg Med Chem Lett. 2016 Aug 1;26(15):3669-74. doi: 10.1016/j.bmcl.2016.05.088. Epub 2016 May 30.

引用本文的文献

1
Methods for Hydroxamic Acid Synthesis.异羟肟酸合成方法。
Curr Org Chem. 2019;23(9):978-993. doi: 10.2174/1385272823666190424142821.
2
Syntheses and Biological Evaluations of Highly Functionalized Hydroxamate Containing and -Methylthio Monobactams as Anti-Tuberculosis and β-Lactamase Inhibitory Agents.含高官能化异羟肟酸和甲硫基单环β-内酰胺类化合物作为抗结核和β-内酰胺酶抑制剂的合成及生物学评价
Medchemcomm. 2016 Jan 1;7(1):141-147. doi: 10.1039/C5MD00340G. Epub 2015 Oct 5.
3
A structure-activity relationship of non-peptide macrocyclic histone deacetylase inhibitors and their anti-proliferative and anti-inflammatory activities.
非肽大环组蛋白去乙酰化酶抑制剂的构效关系及其抗增殖和抗炎活性。
Bioorg Med Chem. 2015 Dec 15;23(24):7543-64. doi: 10.1016/j.bmc.2015.10.045. Epub 2015 Nov 2.
4
Generation and exploration of new classes of antitubercular agents: The optimization of oxazolines, oxazoles, thiazolines, thiazoles to imidazo[1,2-a]pyridines and isomeric 5,6-fused scaffolds.新型抗结核药物的研发:噁唑啉、噁唑、噻唑啉、噻唑类到咪唑并[1,2-a]吡啶和异构 5,6-稠合骨架的优化。
Bioorg Med Chem. 2012 Apr 1;20(7):2214-20. doi: 10.1016/j.bmc.2012.02.025. Epub 2012 Feb 16.
5
Reactions of N-benzyloxycarbamate derivatives with stabilized carbon nucleophiles: a new synthetic approach to polyhydroxamic acids and other hydroxamate-containing mixed ligand systems.N-苄氧羰基氨基甲酸酯衍生物与稳定碳亲核试剂的反应:一种合成聚异羟肟酸及其他含异羟肟酸混合配体体系的新方法。
J Org Chem. 2009 Jan 16;74(2):782-8. doi: 10.1021/jo802410u.