Dalle Valle Raffaele, Capocasale Enzo, Mazzoni Maria Patrizia, Busi Nicola, Sianesi Mario
Department of Surgical Science, University of Parma, Parma, Italy.
Acta Biomed. 2006 Dec;77(3):152-6.
Multiorgan procurement requires good anatomical knowledge and perfect synchronization between surgeons to ensure adequate dissection of visceral vessels. The aim of this article is to assess a technique for pancreas procurement in a multiorgan donor.
starting our program of pancreas transplantation we adopted a technique for "in situ" simultaneous recovery of pancreas, liver and small bowel when indicated. We performed 3/4 of the dissection with an intact donor circulation of the organs so taht the cold ischemia time was kept to a minimum. The technique was used in 18 multiorgan cadaveric donors during a period of 74 months. Seventeen out of 18 pancreatic grafts were transplanted simultaneously with a kidney. The small intestine was transplanted in one case and the liver in 18 cases.
None of the transplanted pancreases sustained serious ischemic or vascular injuries. One pancreatic graft was discarded due to iatrogenic vascular injury during the procurement. Vascular surgical complications included 1 portal thrombosis, 1 iliac graft thrombosis and 1 iliac graft pseudoaneurysm. Pancreas allograft removal was necessary in 4 patients. All the retrived liver and the small intestine were successfully transplanted elsewhere.
All except one of the pancreatic grafts retrived with this technique were of excellent quality. A perfect coordination between the different surgical equipes is mandatory in order to limit the risk of vascular injury, particulary in the presence of anatomical variations.
多器官获取需要具备良好的解剖学知识,且外科医生之间要完美同步,以确保充分解剖内脏血管。本文旨在评估一种在多器官供体中获取胰腺的技术。
在启动胰腺移植项目时,我们采用了一种在有指征时“原位”同时获取胰腺、肝脏和小肠的技术。我们在器官供体循环完整的情况下进行了3/4的解剖操作,以使冷缺血时间降至最短。在74个月的时间里,该技术应用于18例多器官尸体供体。18例胰腺移植物中有17例与肾脏同时移植。1例进行了小肠移植,18例进行了肝脏移植。
所有移植的胰腺均未遭受严重的缺血或血管损伤。1例胰腺移植物在获取过程中因医源性血管损伤而被丢弃。血管外科并发症包括1例门静脉血栓形成、1例髂血管移植物血栓形成和1例髂血管移植物假性动脉瘤。4例患者需要切除胰腺移植物。所有获取的肝脏和小肠均成功移植到其他地方。
用该技术获取的胰腺移植物除1例之外质量均极佳。为限制血管损伤风险,尤其是存在解剖变异的情况下,不同手术团队之间必须完美协作。