Etholm B
Acta Otolaryngol. 1975 Nov-Dec;80(5-6):323-34. doi: 10.3109/00016487509121334.
Inhibition in the medial geniculate body was studied with a double click technique. A conditioning click caused a marked inhibition of field potentials and unit discharges to a subsequent test click. Cyclic inhibition with a period of about 150 ms was seen in the medial geniculate body and the auditory cortex, but not in the inferior colliculus. The postsynaptic excitability was tested by recording from the killed ends of the thalamocortical fibres. A preceding click reduced the direct response to a test stimulus delivered to the medial geniculate body indicating the presence of postsynaptic inhibition. The excitability of the fibres from the inferior colliculus terminating in the medial geniculate body was tested with a modified Wall (1958) method. The results suggest the presence of a presynaptic inhibitory mechanism in the medial geniculate body. The techniques employed do not allow an estimation of the relative contribution of the two inhibitory mechanisms to the inhibition at the medial geniculate level.
采用双声刺激技术对内侧膝状体的抑制作用进行了研究。一个条件性声刺激可显著抑制对随后测试声刺激产生的场电位和单位放电。在内侧膝状体和听觉皮层中观察到周期约为150毫秒的周期性抑制，但在下丘中未观察到。通过记录丘脑皮质纤维的断端来测试突触后兴奋性。一个先行声刺激减少了对施加到内侧膝状体的测试刺激的直接反应，表明存在突触后抑制。用改良的沃尔（1958年）方法测试了终止于内侧膝状体的来自下丘的纤维的兴奋性。结果提示内侧膝状体存在一种突触前抑制机制。所采用的技术无法估计这两种抑制机制对内侧膝状体水平抑制作用的相对贡献。
