早产儿经外周静脉穿刺中心静脉置管（PICC）拔除后导管相关血流感染
Catheter related bloodstream infection following PICC removal in preterm infants.
作者信息
Brooker R W, Keenan W J
机构信息
Department of Pediatrics, Division of Neonatology, Cardinal Glennon Children's Hospital, Saint Louis University School of Medicine, St Louis, MO 63104, USA.
出版信息
J Perinatol. 2007 Mar;27(3):171-4. doi: 10.1038/sj.jp.7211655.
OBJECTIVE
Describe the incidence of catheter-related blood stream infection (CRBSI), following removal of peripherally inserted central venous catheters (PICC) in preterm infants.
STUDY DESIGN
A retrospective cohort study of infants <29 weeks gestational age with a PICC revealed 101 PICCs placed (2159 PICC days). Patients were hospitalized in a level III Neonatal Intensive Care Unit (NICU) between January 2002 and December 2003. Chi(2) analysis was performed.
RESULTS
One infection was detected after the removal of a PICC (1 per 202 days). Ten infants had a CRBSI attributed to a PICC (1 per 216 PICC days). CRBSI during indwelling PICC was associated with increased risk for sepsis evaluation after PICC removal (P<0.05).
CONCLUSIONS
The incidence of CRBSI in the 48 h following PICC removal was not different than the incidence of CRBSI while a PICC was in-dwelling. There was no evidence from this study to support antibacterial prophylaxis before PICC removal.
目的
描述早产儿外周静脉置入中心静脉导管（PICC）拔除后导管相关血流感染（CRBSI）的发生率。
研究设计
一项对孕周小于29周且置入PICC的婴儿进行的回顾性队列研究显示，共置入101根PICC（2159个PICC日）。患者于2002年1月至2003年12月期间在三级新生儿重症监护病房（NICU）住院。进行了卡方分析。
结果
拔除一根PICC后检测到1例感染（每202天1例）。10例婴儿发生归因于PICC的CRBSI（每216个PICC日1例）。PICC留置期间的CRBSI与PICC拔除后脓毒症评估风险增加相关（P<0.05）。
结论
PICC拔除后48小时内CRBSI的发生率与PICC留置期间CRBSI的发生率无差异。本研究没有证据支持在拔除PICC前进行抗菌预防。
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