Mathelin C, Salvador S, Guyonnet J-L
Service de gynécologie-obstétrique, CHRU de Strasbourg, 1, Place de l'Hôpital, Strasbourg Cedex, France.
J Gynecol Obstet Biol Reprod (Paris). 2007 May;36(3):253-9. doi: 10.1016/j.jgyn.2007.01.002. Epub 2007 Feb 21.
The aim of this review is to summarize the current knowledge about axillary recurrences after sentinel lymph node (SLN) biopsy for breast cancer.
A Pubmed search for publications (in English or French) related to breast cancer, SLN and axillary recurrence was carried out from 1995 to 2006.
Under controlled conditions (notably after a learning curve concerning the multidisciplinary team), the SLN procedure proved to be a reliable method for evaluation of axillary nodal status in selected patients with early-stage invasive breast cancer. When the SLN is free of cancer cells, the rate of axillary recurrence varies from 0% to 2% with a follow-up ranging from 14 to 57 months. Recurrence after axillary lymph node dissection is similar. When isolated cancer cells or micrometastases invaded the SLN, the rate of axillary recurrence remains low, but a complete axillary lymph node dissection must be performed to reduce this rate significantly. The use of intraoperative miniaturized gamma cameras could contribute to the optimization of the SLN procedure and to reduce axillary recurrences.
本综述旨在总结目前关于乳腺癌前哨淋巴结（SLN）活检后腋窝复发的相关知识。
对1995年至2006年期间发表在PubMed上的有关乳腺癌、前哨淋巴结和腋窝复发的文献（英文或法文）进行检索。
在可控条件下（特别是在多学科团队经历学习曲线之后），前哨淋巴结活检术被证明是评估部分早期浸润性乳腺癌患者腋窝淋巴结状态的可靠方法。当前哨淋巴结无癌细胞时，腋窝复发率在0%至2%之间，随访时间为14至57个月。腋窝淋巴结清扫术后的复发情况与之相似。当孤立癌细胞或微转移灶侵犯前哨淋巴结时，腋窝复发率仍然较低，但必须进行完整的腋窝淋巴结清扫以显著降低该复发率。术中使用小型伽马相机有助于优化前哨淋巴结活检术并减少腋窝复发。
