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ABO-AK连锁中重组可能存在的性别差异评估。

Evaluation of a possible sex difference in recombination for the ABO-AK linkage.

作者信息

Fenger K, Sorensen S A

出版信息

Am J Hum Genet. 1975 Nov;27(6):784-8.

Abstract

Thirty-five informative families were scored for linkage between the ABO and AK loci. The recombination fractions were estimated separately in females and males and were compared with values reported in the literature. A 1.33:1 ratio for the female:male recombination fraction was obtained by combining all sources, but the difference between the recombination fractions was not significantly different from zero. The present data, combined with those reported earlier, show that the most likely recombination fraction is about 14%.

摘要

对35个信息丰富的家系进行ABO和AK基因座之间的连锁评分。分别在雌性和雄性中估计重组率,并与文献报道的值进行比较。通过合并所有来源,得到雌性与雄性重组率的比例为1.33:1,但重组率之间的差异与零无显著差异。目前的数据与早期报道的数据相结合,表明最可能的重组率约为14%。

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