Stamatelopoulos A, Baltayiannis N, Roussakis A
Department of Thoracic Surgery, Metaxa Cancer Hospital, Piraeus, Greece.
J BUON. 2006 Apr-Jun;11(2):127-42.
Lung carcinogenesis is a field which is yet to be exploited and its molecular mechanisms to be more clearly defined. The goal of this article is to present the major alterations that occur in lung cancer, especially those that happen in the early stages of carcinogenesis. Finally, in this review we present the latest methods that are used to study the cellular/molecular pathophysiology of lung cancer and their clinical appliance.
肺癌发生是一个尚未得到充分探索的领域，其分子机制有待更清晰地界定。本文的目的是阐述肺癌中发生的主要改变，尤其是在致癌作用早期阶段发生的改变。最后，在本综述中，我们介绍了用于研究肺癌细胞/分子病理生理学的最新方法及其临床应用。
