非小细胞肺癌致癌作用的最新研究进展
Recent aspects regarding carcinogenesis in non-small-cell lung cancer.
作者信息
Stamatelopoulos A, Baltayiannis N, Roussakis A
机构信息
Department of Thoracic Surgery, Metaxa Cancer Hospital, Piraeus, Greece.
出版信息
J BUON. 2006 Apr-Jun;11(2):127-42.
PMID:17318962
Abstract
Lung carcinogenesis is a field which is yet to be exploited and its molecular mechanisms to be more clearly defined. The goal of this article is to present the major alterations that occur in lung cancer, especially those that happen in the early stages of carcinogenesis. Finally, in this review we present the latest methods that are used to study the cellular/molecular pathophysiology of lung cancer and their clinical appliance.
摘要
肺癌发生是一个尚未得到充分探索的领域，其分子机制有待更清晰地界定。本文的目的是阐述肺癌中发生的主要改变，尤其是在致癌作用早期阶段发生的改变。最后，在本综述中，我们介绍了用于研究肺癌细胞/分子病理生理学的最新方法及其临床应用。
相似文献
1
Recent aspects regarding carcinogenesis in non-small-cell lung cancer.非小细胞肺癌致癌作用的最新研究进展
J BUON. 2006 Apr-Jun;11(2):127-42.
2
Lung tumours with neuroendocrine differentiation.具有神经内分泌分化的肺肿瘤。
Eur J Cancer. 2009 Sep;45 Suppl 1:251-66. doi: 10.1016/S0959-8049(09)70040-1.
3
Molecular cytogenetic alterations in the early stage at human bronchial epithelial cell carcinogenesis.人支气管上皮细胞癌变早期的分子细胞遗传学改变。
J Cell Biochem Suppl. 1997;28-29:74-80.
4
Genomic instability in patients with non-small cell lung cancer assessed by the arbitrarily primed polymerase chain reaction.通过任意引物聚合酶链反应评估非小细胞肺癌患者的基因组不稳定性。
Cancer Invest. 2008 Apr-May;26(3):262-8. doi: 10.1080/07357900701708385.
5
Mechanisms of Disease: signal transduction in lung carcinogenesis -- a comparison of smokers and never-smokers.疾病机制：肺癌发生中的信号转导——吸烟者与从不吸烟者的比较
Nat Clin Pract Oncol. 2008 Oct;5(10):610-8. doi: 10.1038/ncponc1181. Epub 2008 Jul 15.
6
Sequential occurrence of non-small cell and small cell lung cancer with the same EGFR mutation.非小细胞肺癌和小细胞肺癌先后发生且具有相同的表皮生长因子受体（EGFR）突变
Lung Cancer. 2007 Dec;58(3):411-3. doi: 10.1016/j.lungcan.2007.05.014. Epub 2007 Jun 29.
7
[Problem cases in lung pathology].[肺部病理学中的疑难病例]
Pathologe. 1996 Jan;17(1):98-101.
8
Analysis of SOX4 gene mutation in non-small cell lung cancer tissues.非小细胞肺癌组织中SOX4基因突变分析
Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2007 Oct;24(5):505-9.
9
Overexpression of Pokemon in non-small cell lung cancer and foreshowing tumor biological behavior as well as clinical results.Pokemon在非小细胞肺癌中的过表达及其对肿瘤生物学行为和临床结果的预示作用。
Lung Cancer. 2008 Oct;62(1):113-9. doi: 10.1016/j.lungcan.2008.02.014. Epub 2008 Jun 11.
10
Lung cancer: an ever increasing store of in-depth basic knowledge and the beginning of its clinical application.肺癌：深入的基础知识储备不断增加，且其临床应用已初现端倪。
Oncogene. 2002 Oct 7;21(45):6868-9. doi: 10.1038/sj.onc.1205830.
Zotero 插件