Kaler Sharndeep Norry, Ralph-Campbell Kelli, Pohar Sheri, King Malcolm, Laboucan Chief Rose, Toth Ellen L
Heritage Research Medical Center, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada.
Int J Circumpolar Health. 2006 Dec;65(5):389-402. doi: 10.3402/ijch.v65i5.18139.
Increasing type 2 diabetes in Aboriginal communities across North America raises concerns about metabolic syndrome in these populations. Some prevalence information for American Indians exists, but little has been available for Canada's First Nations.
We screened 60% of the eligible population of a single First Nation in Alberta for diabetes, pre-diabetes, cardiovascular risk, and metabolic syndrome.
NCEP/ATP III and IDF criteria were used to identify metabolic syndrome in participants aged > or = 18; modified NCEP/ATP III criteria were used for participants aged < 18. Logistic regression identified factors associated with the metabolic syndrome.
297 individuals were screened (176 adults, 84 children/adolescents, with complete data). 52.3% of adults had metabolic syndrome using NCEP/ATP III criteria, and 50% using IDF criteria. 40.5% of individuals aged < 18 had the condition. Waist circumference was the most prevalent correlate. Bivariate analysis suggested that age, BMI, weight, Alc, LDL-C, ADA risk score and activity pattern were associated with metabolic syndrome.
Our data represent the first available for Western Cree and are consistent with prevalence reported for Aboriginal populations in Ontario and Manitoba. High rates of obesity, pre-diabetes and metabolic syndrome for participants aged < 18 raise concerns about future prevalence of diabetes and cardiovascular disease.
北美各原住民社区中2型糖尿病发病率不断上升,引发了对这些人群代谢综合征的担忧。关于美国印第安人的一些患病率信息已有报道,但加拿大第一民族的相关信息却很少。
我们对阿尔伯塔省一个第一民族符合条件人群的60%进行了糖尿病、糖尿病前期、心血管风险和代谢综合征筛查。
采用NCEP/ATP III和IDF标准来确定18岁及以上参与者的代谢综合征;对于18岁以下参与者,采用修改后的NCEP/ATP III标准。逻辑回归分析确定与代谢综合征相关的因素。
共筛查了297人(176名成年人,84名儿童/青少年,数据完整)。按照NCEP/ATP III标准,52.3%的成年人患有代谢综合征;按照IDF标准,这一比例为50%。18岁以下人群中,40.5%患有该疾病。腰围是最常见的相关因素。双变量分析表明,年龄、体重指数、体重、糖化血红蛋白、低密度脂蛋白胆固醇、ADA风险评分和活动模式与代谢综合征有关。
我们的数据是关于西克里人的首批可用数据,与安大略省和曼尼托巴省原住民人群的患病率报告一致。18岁以下参与者中肥胖、糖尿病前期和代谢综合征的高发病率引发了对未来糖尿病和心血管疾病患病率的担忧。