Denis D, Dauletbekov D, Alessi G, Chapon F, Girard N
Department of Ophthalmology, North's Hospital, Marseille, France.
J Neuroradiol. 2007 May;34(2):137-40. doi: 10.1016/j.neurad.2007.01.002.
Neuroimaging findings in Duane's retraction syndrome (DRS), through magnetic resonance imaging (MRI), suggest that aplasia of the abducens nerve (VI) can be responsible for several forms of DRS.
Brain MRI was performed in two children of 2.5 and 7 years of age with left sided DRS type II and right sided DRS type I, respectively. 3D T2 weighted images through the brainstem were acquired in order to visualize the cranial nerves especially the abducens (VI) and oculomotor (III) nerves.
The abducens nerve on the affected side could not be observed in these two different types of DRS with normal morphology of the third nerves.
Absence of the VI nerve has been described recently in DRS types I and III only, while DRS type II is usually associated with normal VI nerve on MRI. However our results show that aplasia of the VI nerve can also be seen in DRS type II resulting in new insight of the pathogenesis of this clinical entity.
通过磁共振成像（MRI）对杜安眼球后退综合征（DRS）的神经影像学研究结果表明，外展神经（Ⅵ）发育不全可能是多种形式DRS的病因。
分别对两名2.5岁和7岁的儿童进行脑部MRI检查，两名儿童分别患有左侧Ⅱ型DRS和右侧Ⅰ型DRS。获取通过脑干的三维T2加权图像，以观察颅神经，特别是外展神经（Ⅵ）和动眼神经（Ⅲ）。
在这两种不同类型的DRS中，患侧的外展神经均未观察到，而动眼神经形态正常。
近期报道仅在Ⅰ型和Ⅲ型DRS中存在Ⅵ神经缺失，而Ⅱ型DRS在MRI上通常与正常Ⅵ神经相关。然而，我们的结果显示，Ⅱ型DRS中也可见Ⅵ神经发育不全，这为该临床病症的发病机制提供了新的见解。
