Kothari Mihir
Department of Pediatric Ophthalmology and Strabismus, Bombay City Eye Institute and Research Centre, 5 Victor Villa, Babulnath Road, Mumbai - 400 007, India.
Indian J Ophthalmol. 2007 Mar-Apr;55(2):117-20. doi: 10.4103/0301-4738.30705.
To describe the clinical characteristics of spontaneous, late-onset comitant acute, nonaccommodative esotropia (ANAET) in children.
Clinical characteristics of a cohort of patients under 16 years of age with ANAET were studied retrospectively.
Of 15 patients eight were females. Mean age was 7.15 years (range 2.5-13, SD 3.34). Mean age of the onset of deviation was 3.2 years (range 1.5-9, SD 2.26). Mean duration of strabismus was 36 months (range 3-132, SD 43). History of a precipitating event was present in five patients (33.3%). Mean cycloplegic refraction was 1.84 diopter sphere (range -5.75 to +7.25, SD 3.55). Mean esodeviation for near and distance fixation was 40 prism diopter (range 15-90, SD 23.9). None had near/distance disparity of more than 5 prism diopter. Amblyopia was present in 13 cases (87%). Strabismus surgery was performed for eight patients. Five patients had orthophoria and three were aligned within 8 prisms esodeviation.
ANAET is more common than previously reported, has a variable time of onset and high incidence of amblyopia. Timely management would avert emergence of amblyopia and vertical incomitance thereby promising better binocular outcome.
描述儿童自发性迟发性共同性急性非调节性内斜视（ANAET）的临床特征。
对一组16岁以下ANAET患者的临床特征进行回顾性研究。
15例患者中8例为女性。平均年龄7.15岁（范围2.5 - 13岁，标准差3.34）。平均斜视发病年龄为3.2岁（范围1.5 - 9岁，标准差2.26）。平均斜视持续时间为36个月（范围3 - 132个月，标准差43）。5例患者（33.3%）有诱发事件史。平均睫状肌麻痹验光为球镜1.84屈光度（范围 - 5.75至 + 7.25，标准差3.55）。近距和远距注视时的平均内斜度为40棱镜度（范围15 - 90，标准差23.9）。无一例近距/远距差异超过5棱镜度。13例（87%）存在弱视。8例患者接受了斜视手术。5例患者眼位正，3例在8棱镜度内斜视范围内对齐。
ANAET比先前报道的更常见，发病时间不一，弱视发生率高。及时治疗可避免弱视和垂直斜视的出现，从而有望获得更好的双眼视觉效果。
