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[人工关节置换术后血源性感染及其手术预防]

[Late hematogenic infection of joint replacements and its prevention in surgery].

作者信息

Jahoda D, Simsa J, Nyc O, Pokorný D, Landor I, Tawa N, Sosna A

机构信息

Ortopedická klinika 1. LF UK a FN Motol, Praha.

出版信息

Rozhl Chir. 2006 Nov;85(11):581-5.

PMID:17323552
Abstract

INTRODUCTION

Late hematogenic infections of joint replacements represent a serious complication. The aim of the study is to assess a patient group with late hematgenic infections of allografts and to propose preventive measures.

METHODS

The restrospective study included patients treated for infectious complications of their joint implants in the 1st Orthopaedic Clinic of the 1st LF UK and FN Motol during the 1991-2004 period. The study included 229 patients in total, of which 149 subjects were females and 80 were males. In 123 subjects their hip joint implant infection was managed, in 102 subjects the knee joint endoprosthesis infection and in two subjects the shoulder joint prosthesis infection was managed. The last two subjects sufferred from infections of their elbow joint alloplasty.

RESULTS

Urinary infection or other procedures of urogenital tract were recorded in 37 patients (16.2%). Upper respiratory tract infections preceding deep joint implant infections were reported in 30 subjects (13.1%). Stomatological procedures or oral cavity disorders was diagnosed in 1 subjects (4.8%). Surgical proceudres with suspected bacteriemia was recorded in 6 subjects (2.6%).

CONCLUSION

Late hematological infections of bone replacements are serious complications with imminent medical and economical consequences. The infection may be caused by a variety of conditions and medical procedures connected to bacteriemia. Provided the risk of the joint implant infection is high (immunocompromised patients, "recent" endoprosthesis implantation within the last two years), prophylactic antibiotic medication is strongly recommended in all conditions with increased risk of bacteriemia.

摘要

引言

关节置换术后晚期血源性感染是一种严重的并发症。本研究旨在评估一组接受同种异体移植晚期血源性感染的患者,并提出预防措施。

方法

这项回顾性研究纳入了1991年至2004年期间在布拉格查理大学医学院第一附属医院和Motol大学医院第一骨科诊所接受关节植入物感染并发症治疗的患者。该研究共纳入229例患者,其中149例为女性,80例为男性。123例患者接受了髋关节植入物感染的治疗,102例患者接受了膝关节假体感染的治疗,2例患者接受了肩关节假体感染的治疗。最后2例患者患有肘关节异体成形术感染。

结果

37例患者(16.2%)记录有泌尿系统感染或其他泌尿生殖道手术。30例患者(13.1%)报告在深部关节植入物感染之前有上呼吸道感染。1例患者(4.8%)诊断有口腔手术或口腔疾病。6例患者(2.6%)记录有疑似菌血症的外科手术。

结论

骨置换术后晚期血液感染是严重的并发症,会带来直接的医疗和经济后果。感染可能由多种与菌血症相关的情况和医疗程序引起。如果关节植入物感染风险较高(免疫功能低下患者,过去两年内“近期”植入假体),强烈建议在所有菌血症风险增加的情况下预防性使用抗生素。

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