Malignant pheochromocytoma of the urinary bladder.

This report describes an illustrative case of malignant pheochromocytoma of the urinary bladder in a 28-year old man. A combined-modality treatment plan with partial cystectomy and post-operative radiotherapy and concurrent chemotherapy with single agent cisplatin weekly was performed. Three weeks after completing concurrent chemoradiation the first of four planned cycles of cisplatin 25 mg/m2 and etoposide 100 mg/m2 was administered daily over 3 days. Although there are no controlled series offering proof of benefit, postoperative concurrent chemoradiation followed by chemotherapy alone are reasonable options for patients with residual disease or at high risk for locoregional relapse.