Ashida Takashi, Mayama Takashi, Higashishiba Masaki, Kawanishi Kazunobu, Miyatake Junichi, Tatsumi Yoichi, Kanamaru Akihisa
Division of Hematology, Department of Internal Medicine, Kinki University School of Medicine, 377-2, Ohonohigashi, Osakasayama, Osaka, Japan.
Hematology. 2006 Jun;11(3):179-81. doi: 10.1080/10245330600667492.
A 53-year-old male with myelodysplastic syndrome developed Sweet's syndrome extensively over his left iliac and inguinal regions that was refractory to standard treatment with corticosteroids and chemotherapy, received a stem cell transplant from an HLA-matched unrelated donor, conditioned by reduced-intensity regimen. The patient achieved complete hematological remission, and the cutaneous lesions improved gradually and then disappeared completely despite the patient receiving granulocyte colony-stimulating factor after transplantation and developing acute graft-versus-host disease.
一名53岁患有骨髓增生异常综合征的男性,其左髂部和腹股沟区广泛出现斯威特综合征,对皮质类固醇和化疗的标准治疗无效,接受了来自人类白细胞抗原匹配的无关供体的干细胞移植,采用减低强度预处理方案。患者实现了完全血液学缓解,皮肤病变逐渐改善,尽管移植后接受了粒细胞集落刺激因子并发生了急性移植物抗宿主病,但皮肤病变最终完全消失。