To be or not to be protease activated receptor-1 in activated protein C-initiated endothelial barrier protection?
作者信息
Li Shi-Sheng
出版信息
Crit Care. 2007;11(1):407; author reply 407. doi: 10.1186/cc5149.
Abstract
摘要
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To be or not to be protease activated receptor-1 in activated protein C-initiated endothelial barrier protection?在活化蛋白C启动的内皮屏障保护中，是否存在蛋白酶激活受体-1？
Crit Care. 2007;11(1):407; author reply 407. doi: 10.1186/cc5149.
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本文引用的文献
1
Bench-to-bedside review: the role of activated protein C in maintaining endothelial tight junction function and its relationship to organ injury.
Crit Care. 2006;10(6):239. doi: 10.1186/cc5099.
2
The cytoprotective protein C pathway.细胞保护蛋白C途径。
Blood. 2007 Apr 15;109(8):3161-72. doi: 10.1182/blood-2006-09-003004. Epub 2006 Nov 16.
3
Activated protein C mediates novel lung endothelial barrier enhancement: role of sphingosine 1-phosphate receptor transactivation.活化蛋白C介导新型肺内皮屏障增强：1-磷酸鞘氨醇受体反式激活的作用
J Biol Chem. 2005 Apr 29;280(17):17286-93. doi: 10.1074/jbc.M412427200. Epub 2005 Feb 14.
4
Endothelial barrier protection by activated protein C through PAR1-dependent sphingosine 1-phosphate receptor-1 crossactivation.活化蛋白C通过PAR1依赖性鞘氨醇-1-磷酸受体-1交叉激活实现内皮屏障保护。
Blood. 2005 Apr 15;105(8):3178-84. doi: 10.1182/blood-2004-10-3985. Epub 2004 Dec 30.
5
Activated protein C blocks p53-mediated apoptosis in ischemic human brain endothelium and is neuroprotective.活化蛋白C可阻断缺血性人脑内皮细胞中p53介导的细胞凋亡，具有神经保护作用。
Nat Med. 2003 Mar;9(3):338-42. doi: 10.1038/nm826. Epub 2003 Feb 3.
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