Kabbani Ahmad Toufic, Hammud Hassan Hasan, Ghannoum Amer Mohammed
Natural Science Division, Lebanese American University, Beirut-Lebanon.
Chem Pharm Bull (Tokyo). 2007 Mar;55(3):446-50. doi: 10.1248/cpb.55.446.
Copper and cobalt complexes with 4-chloro-3-nitrobenzoate (ClNBz) and the nitrogen ligands 1,3-diaminopropane (1,3-DAP) or o-phenylenediamine (o-PDA), were prepared and characterized. The complexes [Cu(ClNBz)2(1,3-DAP)] (1), [Cu(ClNBz)(o-PDA)]Cl (2), [Co(ClNBz)2(1,3-DAP)] (3) and [Co(ClNBz)2(o-PDA)2] (4) were characterized by FTIR, UV-Visible absorption, elemental analysis and thermal analysis. Complex [Cu(ClNBz)(o-PDA)]Cl (2) shows high antibacterial activity as indicated by its ability to inhibit the growth of Staphylococcus aureus, Enterococcus faecalis.
制备并表征了铜和钴与4-氯-3-硝基苯甲酸酯（ClNBz）以及氮配体1,3-二氨基丙烷（1,3-DAP）或邻苯二胺（o-PDA）形成的配合物。通过傅里叶变换红外光谱（FTIR）、紫外可见吸收光谱、元素分析和热分析对配合物[Cu(ClNBz)2(1,3-DAP)]（1）、[Cu(ClNBz)(o-PDA)]Cl（2）、[Co(ClNBz)2(1,3-DAP)]（3）和[Co(ClNBz)2(o-PDA)2]（4）进行了表征。配合物[Cu(ClNBz)(o-PDA)]Cl（2）表现出较高的抗菌活性，这体现在其对金黄色葡萄球菌、粪肠球菌生长的抑制能力上。
