• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Successful treatment of primary Sjögren's syndrome with chronic natural killer lymphocytosis by high-dose prednisolone and indomethacin farnesil.

作者信息

Fujita Yoshimasa, Fujii Takao, Takeda Naho, Tanaka Masao, Mimori Tsuneyo

机构信息

Department of Rheumatology and Clinical Immunology, Graduate School of Medicine, Kyoto University, Kyoto, USA.

出版信息

Intern Med. 2007;46(5):251-4. doi: 10.2169/internalmedicine.46.1881. Epub 2007 Mar 1.

DOI:10.2169/internalmedicine.46.1881
PMID:17329922
Abstract

We report a patient with Sjögren's syndrome and chronic natural killer lymphocytosis, who developed severe neutropenia, autoimmune hemolytic anemia, and immune thrombocytopenia. High-dose prednisolone therapy improved the hemolytic anemia and thrombocytopenia, but not the CD16(+) CD56(-) NK lymphocytosis completely. Interestingly, indomethacin farnesil (a prodrug of indomethacin) was effective for myalgia and also decreased the number of CD16(+) CD56(-) NK cells. NK lymphocytosis is rarely associated with autoimmune disease, but the combination of indomethacin and steroid therapy may have a favorable effect for such patients.

摘要

相似文献

1
Successful treatment of primary Sjögren's syndrome with chronic natural killer lymphocytosis by high-dose prednisolone and indomethacin farnesil.
Intern Med. 2007;46(5):251-4. doi: 10.2169/internalmedicine.46.1881. Epub 2007 Mar 1.
2
Coexisting ankylosing spondylitis and Sjogren's syndrome: a case report.强直性脊柱炎与干燥综合征并存：一例报告
Rheumatol Int. 2005 Aug;25(6):478-80. doi: 10.1007/s00296-005-0598-6. Epub 2005 Mar 11.
3
Steroid-resistant protein-losing gastroenteropathy complicated with Sjögren's syndrome successfully treated with mizoribine.用咪唑立宾成功治疗的并发干燥综合征的类固醇抵抗性蛋白丢失性胃肠病
Mod Rheumatol. 2018 Jul;28(4):716-720. doi: 10.3109/14397595.2016.1145570. Epub 2016 Apr 4.
4
Successful treatment with intravenous immunoglobulin of severe thrombocytopenia complicated in primary Sjögren's syndrome.静脉注射免疫球蛋白成功治疗原发性干燥综合征合并严重血小板减少症。
Rheumatol Int. 2012 May;32(5):1353-5. doi: 10.1007/s00296-010-1395-4. Epub 2010 Mar 17.
5
Autoimmune hepatitis concomitant with hypergammaglobulinemic purpura, immune thrombocytopenia, and Sjögren's syndrome.自身免疫性肝炎合并高球蛋白血症性紫癜、免疫性血小板减少症和干燥综合征。
Intern Med. 2001 Apr;40(4):308-11. doi: 10.2169/internalmedicine.40.308.
6
Sensorineural hearing loss as the first manifestation of Sjögren's syndrome.感音神经性听力损失作为干燥综合征的首发表现
Rev Assoc Med Bras (1992). 2017 Jan 1;63(1):7-9. doi: 10.1590/1806-9282.63.01.7.
7
Severe autoimmune hemolytic anemia associated with IgM warm auto-antibodies in primary Sjögren's syndrome.原发性干燥综合征相关 IgM 温自身抗体致严重自身免疫性溶血性贫血。
Int J Rheum Dis. 2010 Feb 1;13(1):94-6. doi: 10.1111/j.1756-185X.2009.01450.x.
8
A case of primary Sjögren's syndrome associated with low titer cold agglutinin disease.一例原发性干燥综合征合并低滴度冷凝集素病。
Clin Exp Rheumatol. 2002 Jul-Aug;20(4):577-8.
9
Autoimmune haemolytic anaemia as an initial presentation of primary Sjögren syndrome.自身免疫性溶血性贫血作为原发性干燥综合征的首发表现。
Intern Med J. 2014 Dec;44(12a):1259-61. doi: 10.1111/imj.12611.
10
Sjögren's syndrome complicated with autoimmune hepatitis and antiphospholipid antibody syndrome.
Intern Med. 2000 Jan;39(1):73-6. doi: 10.2169/internalmedicine.39.73.

引用本文的文献

1
Scleritis and multiple systemic autoimmune manifestations in chronic natural killer cell lymphocytosis associated with elevated TCRalpha/beta+CD3+CD4-CD8- double-negative T cells.慢性自然杀伤细胞淋巴组织增生症伴 TCRα/β+CD3+CD4-CD8-双阴性 T 细胞增高，伴发巩膜炎和多种系统性自身免疫表现。
Br J Ophthalmol. 2010 Jun;94(6):748-52. doi: 10.1136/bjo.2009.171264.