Riesen W F
Institut für Klinische Chemie und Hämatologie, Kantons St. Gallen.
Schweiz Rundsch Med Prax. 1992 Jan 14;81(3):49-54.
The determination of total cholesterol (and eventually triglycerides) is sufficient for screening purposes. Values below 5.2 mmol/l (200 mg/dl) may be considered ideal, where as higher values need a differentiated diagnostic evaluation which should include the measurement of triglycerides and of HDL-cholesterol after 12 h fasting. The decision for a drug therapy should consider other risk factors such as hypertension, smoking, diabetes mellitus, male sex, positive family anamnesis for myocardial infarction already existing and coronary heart disease. The treatment of a dyslipoproteinemia should always start with dietary measures. If these are not successful, a lipid-regulating drug therapy should be started in addition to the diet. The choice of the drug depends on the type of dyslipoproteinemia and its genetic and metabolic cause and on the individual side effects.
测定总胆固醇（最终还有甘油三酯）足以用于筛查目的。低于5.2毫摩尔/升（200毫克/分升）的值可被视为理想值，而较高的值则需要进行鉴别诊断评估，其中应包括在禁食12小时后测量甘油三酯和高密度脂蛋白胆固醇。决定药物治疗时应考虑其他风险因素，如高血压、吸烟、糖尿病、男性、心肌梗死或冠心病的家族病史阳性。血脂异常血症的治疗应始终从饮食措施开始。如果这些措施不成功，则应在饮食基础上开始使用调脂药物治疗。药物的选择取决于血脂异常血症的类型及其遗传和代谢原因以及个体副作用。
