Houriet P
Hôpital orthopédique, Lausanne.
Schweiz Rundsch Med Prax. 1992 Jan 21;81(4):78-83.
From 1964-1987 we have examined 31 patients suspected to have gaseous gangrene. The diagnosis was confirmed 13 times on clinical and microbiologic grounds. 61% of the patients underwent amputation, 28% died. On the basis of this experience we have tried to define a therapeutic attitude. We recommend an adequate debridement, i.e. the removal of necrotic tissue and drainage of the wound, microbiological investigations and the administration of antibiotics before hyperbaric oxygen treatment is begun (2-3 treatments over 3 days).
1964年至1987年间,我们检查了31名疑似气性坏疽的患者。其中13例经临床和微生物学检查确诊。61%的患者接受了截肢手术,28%的患者死亡。基于这一经验,我们试图确定一种治疗方法。我们建议进行充分的清创术,即切除坏死组织并对伤口进行引流,在开始高压氧治疗(3天内进行2至3次治疗)之前进行微生物学检查并使用抗生素。