Neville Julie A, Hancox John G, Williford Phillip M, Yosipovitch Gil
Department of Dermatology, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157-1071, USA.
Cutis. 2007 Jan;79(1):37-40.
The ulcerative variant of lichen planus (LP) commonly involves the oral mucosa but is uncommon and difficult to treat when located on other areas. We describe an unusual case of ulcerative LP involving several surfaces, including the palms and scrotum, in a 50-year-old man with hepatitis C. The patient was recalcitrant to treatment with conventional therapy but obtained clearance with a sustained response using low molecular weight heparin (LMWH). This treatment is an option for patients with LP who are not ideal candidates for standard therapy.
扁平苔藓（LP）的溃疡性变体通常累及口腔黏膜，但位于其他部位时并不常见且难以治疗。我们描述了一例罕见的溃疡性LP病例，累及一名50岁丙型肝炎男性的多个部位，包括手掌和阴囊。该患者对传统治疗耐药，但使用低分子量肝素（LMWH）获得持续缓解而清除病灶。对于那些不适合标准治疗的LP患者，这种治疗是一种选择。
