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全膝关节置换术后因感染失败后采用长髓内钉进行膝关节融合术。手术技术。

Arthrodesis of the knee with a long intramedullary nail following the failure of a total knee arthroplasty as the result of infection. Surgical technique.

作者信息

Bargiotas Konstantinos, Wohlrab David, Sewecke Jeffrey J, Lavinge Gregory, DeMeo Patrick J, Sotereanos Nicholas G

机构信息

Department of Orthopaedics, Allegheny General Hospital, Pittsburgh, Pennsylvania, USA.

出版信息

J Bone Joint Surg Am. 2007 Mar;89 Suppl 2 Pt.1:103-10. doi: 10.2106/JBJS.F.01125.

Abstract

BACKGROUND

Knee arthrodesis can be an effective treatment option for relieving pain and restoring some function after the failure of a total knee arthroplasty as the result of infection. The purpose of the present study was to review the outcome of a staged approach for arthrodesis of the knee with a long intramedullary nail after the failure of a total knee arthroplasty as the result of infection.

METHODS

We reviewed the results for twelve patients who underwent knee arthrodesis after the removal of a prosthesis because of infection. The study group included seven women and five men who had an average age of sixty-eight years at the time of the arthrodesis. All patients were managed with a staged protocol. Implant removal, débridement, and insertion of antibiotic cement spacers was followed by the administration of systemic antibiotics. Provided that clinical and laboratory data suggested eradication of the infection, arthrodesis of the affected knee with use of a long intramedullary nail was carried out. Clinical and laboratory evaluation and radiographic analysis were performed after an average duration of follow-up of 4.1 years.

RESULTS

Solid union was achieved in ten of the twelve knees. The average time to union was 5.5 months. One patient had an above-the-knee amputation because of recurrence of infection. In another patient, nail breakage occurred three years following implantation. The average limb-length discrepancy was 5.5 cm. The mean Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score improved from 41 to 64 points. None of the seven patients who underwent arthrodesis with a technique involving convex-to-concave reamers had a complication, and the average time to union for these seven patients was shorter than that for the remaining five patients (4.3 compared with 7.4 months).

CONCLUSIONS

We believe that obtaining large surfaces of bleeding contact bone during arthrodesis following staged treatment of an infection at the site of a failed total knee arthroplasty contributes to stability and enhances bone-healing. Staged arthrodesis with use of a long intramedullary nail and convex-to-concave preparation of bone ends provided a painless functional gait with low complication and reoperation rates in this challenging group of patients.

摘要

背景

膝关节融合术可作为全膝关节置换术后因感染失败而缓解疼痛和恢复部分功能的有效治疗选择。本研究的目的是回顾因感染导致全膝关节置换失败后,采用长髓内钉分期治疗膝关节融合术的结果。

方法

我们回顾了12例因感染而取出假体后接受膝关节融合术患者的结果。研究组包括7名女性和5名男性,膝关节融合术时的平均年龄为68岁。所有患者均采用分期方案治疗。在取出植入物、清创并插入抗生素骨水泥间隔物后,给予全身抗生素治疗。如果临床和实验室数据表明感染已根除,则使用长髓内钉对患膝进行融合术。平均随访4.1年后进行临床和实验室评估以及影像学分析。

结果

12例膝关节中有10例实现了牢固愈合。平均愈合时间为5.5个月。1例患者因感染复发接受了膝上截肢。另1例患者在植入后3年发生髓内钉断裂。平均肢体长度差异为5.5厘米。西安大略和麦克马斯特大学骨关节炎指数(WOMAC)平均评分从41分提高到64分。采用凸面到凹面扩孔钻技术进行膝关节融合术的7例患者均未出现并发症,这7例患者的平均愈合时间短于其余5例患者(分别为4.3个月和7.4个月)。

结论

我们认为,在全膝关节置换失败部位感染的分期治疗后进行膝关节融合术时,获得大面积有出血接触的骨面有助于稳定并促进骨愈合。在这组具有挑战性的患者中,采用长髓内钉分期膝关节融合术和骨端凸面到凹面的处理方法,可提供无痛的功能性步态,并发症和再次手术率较低。

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